BRENDA - Reference to 1.6.1.2; Id = 725514

additional information

overexpression and knockdown of the enzyme in carcinoma cells, phenotypes, overview

Mus musculus

mitochondrial inner membrane

-

Mus musculus

5743

-

NADPH + NAD+

Mus musculus

-

NADP+ + NADH

-

r

NADPH + NAD+

Mus musculus C57/BL6J

-

NADP+ + NADH

-

r

Mus musculus

-

Mus musculus C57/BL6J

-

melanoma cell

-

Mus musculus

-

RCC 786-O cell

-

Mus musculus

-

renal carcinoma cell

-

Mus musculus

-

SK-MEL-5 cell

-

Mus musculus

-

NADPH + NAD+

-

725514

Mus musculus

NADP+ + NADH

-

r

NADPH + NAD+

-

725514

Mus musculus C57/BL6J

NADP+ + NADH

-

r

nicotinamide nucleotide transhydrogenase

-

Mus musculus

NNT

-

Mus musculus

additional information

overexpression and knockdown of the enzyme in carcinoma cells, phenotypes, overview

Mus musculus

mitochondrial inner membrane

-

Mus musculus

5743

-

NADPH + NAD+

Mus musculus

-

NADP+ + NADH

-

r

NADPH + NAD+

Mus musculus C57/BL6J

-

NADP+ + NADH

-

r

melanoma cell

-

Mus musculus

-

RCC 786-O cell

-

Mus musculus

-

renal carcinoma cell

-

Mus musculus

-

SK-MEL-5 cell

-

Mus musculus

-

NADPH + NAD+

-

725514

Mus musculus

NADP+ + NADH

-

r

NADPH + NAD+

-

725514

Mus musculus C57/BL6J

NADP+ + NADH

-

r

malfunction

knockdown of the enzyme inhibits the contribution of glutamine to the tricarbonic acid cycle and activates glucose catabolism in SkMel5 melanoma cells. The increase in glucose oxidation partially occurs through pyruvate carboxylase and renders NNT knockdown cells more sensitive to glucose deprivation. Importantly, knocking down NNT inhibits reductive carboxylation in SkMel5 and 786-O renal carcinoma cells. Overexpression of NNT is sufficient to stimulate glutamine oxidation and reductive carboxylation, whereas it inhibits glucose catabolism in the TCA cycle, with impairment of the NAD(P)H/NAD(P)+ ratios

Mus musculus

physiological function

nicotinamide nucleotide transhydrogenase is a mitochondrial enzyme that transfers reducing equivalents from NADH to NADPH

Mus musculus

malfunction

knockdown of the enzyme inhibits the contribution of glutamine to the tricarbonic acid cycle and activates glucose catabolism in SkMel5 melanoma cells. The increase in glucose oxidation partially occurs through pyruvate carboxylase and renders NNT knockdown cells more sensitive to glucose deprivation. Importantly, knocking down NNT inhibits reductive carboxylation in SkMel5 and 786-O renal carcinoma cells. Overexpression of NNT is sufficient to stimulate glutamine oxidation and reductive carboxylation, whereas it inhibits glucose catabolism in the TCA cycle, with impairment of the NAD(P)H/NAD(P)+ ratios

Mus musculus

physiological function

nicotinamide nucleotide transhydrogenase is a mitochondrial enzyme that transfers reducing equivalents from NADH to NADPH

Mus musculus

742433

Scott

Association of adrenal insuff ...

Homo sapiens

Eur. J. Endocrinol.

176

C1-C2

2017

-

1

-

1

-

1

-

2

-

1

-

1

-

742757

Leskov

Nicotinamide nucleotide trans ...

Mus musculus, Mus musculus C57/BL6J

J. Am. Soc. Hypertens.

11

110-121

2017

-

1

-

2

-

61

-

2

-

2

-

1

-

2

-

2

-

2

-

743367

Kaemaeraeinen

Pyridine nucleotide transhydr ...

Synechocystis sp.

New Phytol.

214

194-204

2017

-

1

-

1

-

2

-

1

2

-

1

-

1

-

1

-

2

-

742631

Metherell

three-dimensional model of hu ...

Homo sapiens

Hum. Mutat.

37

1074-1084

2016

-

15

-

2

-

1

-

1

-

1

2

-

15

-

2

-

1

-

1

-

742893

Ronchi

The contribution of nicotinam ...

Mus musculus

J. Biol. Chem.

291

20173-20187

2016

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

2

-

1

-

741801

Fujisawa

Impact of a novel homozygous ...

Homo sapiens

BBA Clin.

3

70-78

2015

-

1

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

742241

Nickel

Reversal of mitochondrial tra ...

Mus musculus

Cell Metab.

22

472-484

2015

-

1

-

1

-

4

-

2

-

2

-

2

-

1

-

1

-

2

-

2

-

742520

Jackson

Review and Hypothesis. New in ...

Bos taurus, Entamoeba histolytica, Rhodospirillum rubrum, Thermus thermophilus

FEBS Lett.

589

2027-2033

2015

-

4

-

4

-

4

-

4

-

4

-

4

-

4

-

743069

Weinberg-Shukron

Combined mineralocorticoid an ...

Homo sapiens

J. Med. Genet.

52

636-641

2015

-

1

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

2

-

1

-

742857

Lopert

Nicotinamide nucleotide trans ...

Rattus norvegicus

J. Biol. Chem.

289

15611-15620

2014

-

1

-

1

-

1

-

2

-

2

-

2

-

1

-

1

-

2

-

2

-

2

-

743010

Yamauchi

Enhanced acetic acid and succ ...

Escherichia coli

J. Gen. Appl. Microbiol.

60

112-118

2014

-

1

-

1

-

4

-

1

-

2

-

1

-

1

-

1

-

725068

Ronchi

A spontaneous mutation in the ...

Mus musculus, Mus musculus C57/BL6J

Free Radic. Biol. Med.

63

446-456

2013

-

1

-

2

-

61

-

2

-

2

-

1

-

1

-

1

-

2

-

2

-

2

-

1

-

1

-

2

-

725514

Gameiro

Cofactor balance by nicotinami ...

Mus musculus, Mus musculus C57/BL6J

J. Biol. Chem.

288

12967-12977

2013

-

1

-

1

-

2

-

61

-

4

-

2

-

2

-

1

-

1

-

2

-

4

-

2

-

2

-

742841

Gameiro

Cofactor balance by nicotinam ...

Homo sapiens

J. Biol. Chem.

288

12967-12977

2013

-

1

-

1

-

1

-

4

-

1

-

2

-

1

-

1

-

4

-

1

-

2

-

743045

Vandock

-

Effects of 20-hydroxyecdysone ...

Manduca sexta

J. Insect Sci.

13

0000

2013

2

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

724435

Yin

Silencing of nicotinamide nucl ...

Rattus norvegicus

Biochim. Biophys. Acta

1817

401-409

2012

1

-

1

-

1

-

1

-

1

-

2

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

2

-

2

-

724953

Ripoll

Nicotinamide nucleotide transh ...

Mus musculus, Mus musculus C3H/HeJ, Mus musculus C57/BL6J

FASEB J.

26

3550-3562

2012

-

1

-

1

-

1

-

62

-

12

-

2

-

1

-

1

-

1

-

12

-

2

-

734755

Meimaridou

Mutations in NNT encoding nico ...

Homo sapiens

Nat. Genet.

44

740-742

2012

-

8

-

1

-

1

-

1

-

2

-

1

-

2

-

8

-

1

-

1

-

2

-

1

-

2

-

725679

Vandock

Phospholipid dependence of the ...

Manduca sexta

J. Membr. Biol.

242

89-94

2011

2

-

2

-

1

-

3

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

711287

Sheeran

Diminished NADPH transhydrogen ...

Homo sapiens

Biochim. Biophys. Acta

1797

1138-1148

2010

1

-

3

-

2

-

1

-

2

-

1

-

2

-

2

-

2

-

1

-

3

-

2

-

1

-

1

-

2

-

2

-

1

-

1

-

711879

Yousuf

Localization and targeting of ...

Entamoeba histolytica

Eukaryot. Cell

9

926-933

2010

-

1

-

6

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

6

-

1

-

1

-

1

-

1

-

696513

Olgun

Converting NADH to NAD+ by nic ...

Caenorhabditis elegans, Macaca mulatta, Mus musculus

Biogerontology

10

531-534

2009

-

1

-

3

-

3

-

1

-

3

-

6

-

1

-

3

-

1

-

3

-

686611

Mercer-Haines

Hymenolepis diminuta: mitochon ...

Hymenolepis diminuta

Exp. Parasitol.

119

24-29

2008

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

695903

Vandock

Midgut mitochondrial transhydr ...

Manduca sexta

Arch. Insect Biochem. Physiol.

69

118-126

2008

-

2

-

2

-

4

-

3

-

2

-

1

-

1

-

1

-

2

-

2

-

3

-

2

-

1

-

1

-

684605

Kabus

Expression of the Escherichia ...

Escherichia coli

Appl. Microbiol. Biotechnol.

75

47-53

2007

-

1

-

1

-

1

-

3

-

2

-

1

-

1

-

1

-

1

-

2

-

686316

Aston-Mourney

Increased nicotinamide nucleot ...

Mus musculus

Diabetologia

50

2476-2485

2007

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

672355

Rydstroem

Mitochondrial NADPH transhydro ...

Caenorhabditis elegans, Mus musculus

Biochim. Biophys. Acta

1757

721-726

2006

-

2

-

8

-

2

-

2

-

2

-

677229

Rydstroem

Mitochondrial transhydrogenase ...

Mus musculus

Trends Biochem. Sci.

31

355-358

2006

-

1

-

1

-

1

-

1

-

1

-

673613

Whitehead

Zinc ions selectively inhibit ...

Rhodospirillum rubrum

FEBS Lett.

579

2863-2867

2005

-

2

-

1

-

3

-

1

-

2

-

1

-

1

-

673787

Arkblad

A Caenorhabditis elegans mutan ...

Caenorhabditis elegans

Free Radic. Biol. Med.

38

1518-1525

2005

-

1

-

1

-

2

-

1

-

2

-

657959

Sundaresan

Conformational change in the N ...

Rhodospirillum rubrum

Biochemistry

42

12143-12153

2003

-

1

-

1

-

1

-

2

-

1

-

2

-

2

-

1

2

1

-

1

-

1

-

1

-

2

-

659243

Singh

Interactions between transhydr ...

Homo sapiens, Rhodospirillum rubrum

J. Biol. Chem.

278

33208-33216

2003

2

-

2

1

-

2

-

2

-

2

-

1

-

1

-

8

2

-

4

-

2

-

2

4

2

1

-

2

-

2

-

1

-

1

-

8

2

-

657928

Jackson

The alternating site, binding ...

Bos taurus, Entamoeba histolytica, Escherichia coli, Homo sapiens, Rhodospirillum rubrum

Biochemistry

41

4173-4185

2002

-

3

-

2

-

6

-

5

-

5

-

10

4

-

10

-

10

3

-

2

-

6

-

5

-

10

4

-

658473

Arkblad

Expression of proton-pumping n ...

Caenorhabditis elegans, Homo sapiens, Mus musculus

Comp. Biochem. Physiol. B

133

13-21

2002

3

-

3

-

3

-

6

-

21

-

6

-

3

-

6

-

3

-

6

-

3

-

3

-

21

-

6

-

659015

Hickman

Link between the membrane-boun ...

Rhodobacter sphaeroides

J. Bacteriol.

184

400-409

2002

-

1

-

1

-

1

-

1

-

1

-

2

-

3

-

2

-

1

2

-

1

-

1

-

1

-

2

-

3

-

659181

Weston

The membrane-peripheral subuni ...

Entamoeba histolytica

J. Biol. Chem.

277

26163-26170

2002

-

1

-

1

-

3

1

-

2

-

1

-

1

2

1

-

2

-

1

2

-

1

-

3

1

-

1

-

1

2

1

-

392673

Weston

The unusual transhydrogenase o ...

Entamoeba histolytica

FEBS Lett.

488

51-54

2001

-

1

-

2

-

4

-

1

-

1

-

2

-

4

-

1

4

-

2

-

1

-

1

-

2

-

392668

Bizouarn

Proton translocating nicotinam ...

Bos taurus, Escherichia coli, Rhodospirillum rubrum

Biochim. Biophys. Acta

1457

211-228

2000

-

3

-

3

-

3

2

-

12

-

12

-

3

2

-

735294

White

The high-resolution structure ...

Homo sapiens

Structure

8

1-12

2000

-

1

-

2

-

1

-

4

-

1

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

2

-

1

-

392666

Peake

A catalytically active complex ...

Homo sapiens, Rhodospirillum rubrum

Biochim. Biophys. Acta

1411

159-169

1999

-

2

-

1

-

2

-

2

-

2

-

8

-

2

8

-

1

-

2

-

2

-

392661

Bizouarn

Mutations at tyrosine-235 in t ...

Bos taurus, Rhodospirillum rubrum

Biochim. Biophys. Acta

1320

265-274

1997

-

1

-

2

-

2

-

1

-

2

1

-

8

-

1

8

-

2

-

1

-

2

1

-

392659

Diggle

Properties of the purified, re ...

Rhodospirillum rubrum

Eur. J. Biochem.

241

162-170

1996

-

1

-

3

-

1

-

1

-

2

-

4

-

1

4

-

1

-

1

-

2

-

392660

Diggle

Mutation of Tyr235 in the NAD( ...

Rhodospirillum rubrum

J. Biol. Chem.

271

10109-10115

1996

-

1

-

2

-

5

-

3

-

4

-

1

4

-

2

-

5

-

392658

Hu

Characterization of the intera ...

Escherichia coli

Biochim. Biophys. Acta

1229

64-72

1995

-

7

6

-

1

-

1

-

1

-

1

-

1

-

4

-

4

-

7

-

6

-

1

-

1

-

1

-

1

-

392657

Fristedt

Evidence for a nicotineamide n ...

Escherichia coli, Klebsiella pneumoniae

Biochem. Biophys. Res. Commun.

198

928-932

1994

-

3

-

2

1

-

2

-

1

-

4

1

-

1

-

8

2

-

8

-

3

2

-

2

1

-

1

-

4

1

-

1

-

392656

Yamaguchi

Energy-transducing nicotinamid ...

Bos taurus

J. Biol. Chem.

268

17871-17877

1993

-

2

-

1

-

1

-

1

-

1

-

4

-

4

-

2

-

1

-

1

-

392594

Jackson

Proton-translocating transhydr ...

Escherichia coli, Mammalia

Biochem. Soc. Trans.

19

573-575

1991

-

2

-

3

-

3

-

2

-

8

-

8

-

2

-

3

-

2

-

392597

Yamaguchi

Mitochondrial energy-linked ni ...

Bos taurus

J. Biol. Chem.

266

5728-5735

1991

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

392600

Yamaguchi

Mitochondrial nicotinamide nuc ...

Bos taurus

Biochemistry

28

6050-6056

1989

-

2

-

1

-

1

-

4

-

4

-

2

-

1

-

392601

Yamaguchi

Amino acid sequence of the sig ...

Bos taurus

Biochem. Biophys. Res. Commun.

157

24-29

1988

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

392602

Hoek

Physiological roles of nicotin ...

Mammalia

Biochem. J.

254

1-10

1988

-

4

-

1

-

2

-

2

-

3

-

4

-

4

-

4

-

1

-

2

-

3

-

392603

Yamaguchi

The primary structure of the m ...

Bos taurus

J. Biol. Chem.

263

2761-2767

1988

-

1

-

1

-

2

-

1

-

1

-

4

-

1

4

-

1

-

2

-

1

-

392604

Persson

Energy-linked nicotinamide nuc ...

Bos taurus

Arch. Biochem. Biophys.

259

341-349

1987

-

2

-

3

-

2

-

1

-

1

-

4

-

4

-

2

-

3

-

1

-

1

-

392605

Weis

The orientation of transhydrog ...

Rattus norvegicus

Arch. Biochem. Biophys.

257

424-429

1987

-

1

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

1

-

392606

Eytan

Energy-linked nicotinamide-nuc ...

Bos taurus

J. Biol. Chem.

262

5015-5019

1987

1

-

1

-

1

-

4

-

1

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4

-

1

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392607

Eytan

Energy-linked nicotinamide-nuc ...

Bos taurus

J. Biol. Chem.

262

5008-5014

1987

1

-

1

-

1

-

1

-

4

-

1

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4

-

1

-

1

-

392608

Persson

Evidence for a role of a vicin ...

Bos taurus

Biochem. Biophys. Res. Commun.

142

573-578

1987

-

3

-

1

-

1

-

1

-

3

-

4

-

4

-

3

-

1

-

1

-

3

-

392653

Rydström

-

Transhydrogenases linked to py ...

Bos taurus, Mammalia

Pyridine Nucleotide Coenzymes, Chem. Biochem. Med. Aspects (Dolphin, D. , Poulson, R. , Avramovic, O. , eds. ) Wiley and Sons, New York

2B

433-461

1987

-

2

-

2

-

2

-

8

-

8

-

2

-

2

-

392609

Moody

-

Identification of the nicotina ...

Rattus norvegicus

Biochem. Soc. Trans.

14

1210-1212

1986

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

1

-

1

-

1

-

392610

Clarke

Nucleotide sequence of the pnt ...

Escherichia coli

Eur. J. Biochem.

158

647-653

1986

-

1

-

2

-

1

-

1

-

1

-

4

-

1

4

-

2

-

1

-

1

-

392611

Wu

Purification and reconstitutio ...

Bos taurus

Methods Enzymol.

126

353-360

1986

-

2

-

2

-

1

-

1

2

1

-

4

-

4

-

2

-

1

2

1

-

392612

Nore

Synthesis of pyrophosphate cou ...

Rhodospirillum rubrum

FEBS Lett.

200

133-138

1986

-

1

-

1

-

3

-

1

-

4

-

4

-

1

-

1

-

1

-

392613

Clarke

Expression of the cloned subun ...

Escherichia coli

FEBS Lett.

200

23-26

1986

-

1

-

1

-

1

-

4

-

1

4

-

1

-

392614

Yamaguchi

Mitochondrial nicotinamide nuc ...

Bos taurus

Arch. Biochem. Biophys.

243

20-27

1985

-

3

-

1

-

1

-

1

-

4

-

4

-

3

-

1

-

1

-

392615

Phelps

Mitochondrial nicotinamide nuc ...

Bos taurus

Arch. Biochem. Biophys.

243

298-304

1985

-

2

1

-

1

-

1

-

1

-

4

-

4

-

2

-

2

1

-

1

-

1

-

392616

Carlenor

Affinity chromatography of mit ...

Bos taurus, Rattus norvegicus

Anal. Biochem.

148

518-523

1985

-

2

-

2

-

2

-

2

1

-

8

-

8

-

2

-

2

-

2

1

-

392617

Phelps

Mitochondrial nicotinamide nuc ...

Bos taurus

Biochemistry

24

3503-3507

1985

-

1

-

1

-

1

-

1

-

5

-

5

-

1

-

1

-

1

-

392620

Kozlov

The interaction of mitochondri ...

Bos taurus

Eur. J. Biochem.

145

413-416

1984

-

4

-

1

-

1

-

1

-

4

-

4

-

4

-

1

-

1

-

392621

Phelps

Interaction of purified nicoti ...

Bos taurus

Biochemistry

23

4475-4480

1984

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

392622

Persson

Energy-linked nicotinamide nuc ...

Bos taurus

J. Biol. Chem.

259

8626-8632

1984

-

1

-

2

-

2

-

1

-

2

1

-

4

-

4

-

1

-

2

-

1

-

2

1

-

392623

Pennington

Reconstituted mitochondrial tr ...

Bos taurus

FEBS Lett.

164

345-349

1983

-

1

-

2

-

2

-

1

2

-

4

-

4

-

1

-

2

-

1

2

-

392624

Moody

Inhibition of nicotinamide nuc ...

Rattus norvegicus

Biochem. J.

209

889-892

1983

-

2

-

1

-

1

-

1

-

4

-

4

-

2

-

1

-

1

-

392625

Wu

Subunit structure of submitoch ...

Bos taurus

J. Biol. Chem.

258

7847-7851

1983

-

1

-

1

-

2

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

1

-

392626

Enander

Energy-linked nicotinamide nuc ...

Bos taurus

J. Biol. Chem.

257

14760-14766

1982

-

6

1

-

1

-

1

-

1

-

4

1

-

4

-

6

1

6

1

-

1

-

1

-

392628

Wu

Stereochemistry of NADPH leads ...

Bos taurus

J. Biol. Chem.

257

11680-11683

1982

-

1

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

392629

Wu

An improved method for the pur ...

Bos taurus

J. Biol. Chem.

257

4052-4055

1982

-

2

-

2

-

1

-

2

4

-

4

-

4

-

2

-

1

-

2

4

-

392652

Fisher

-

Membrane-bound pyridine dinucl ...

Bos taurus, Mammalia

The Pyridine Nucleotide Coenzymes (Everse, J. , Andersson, B. , You, K. S. , eds. ) Academic Press, New York

279-324

1982

-

2

-

2

-

2

-

8

-

8

-

2

-

2

-

392630

Phelps

Inhibition of the mitochondria ...

Bos taurus

J. Biol. Chem.

256

8217-8221

1981

-

2

-

1

-

1

-

1

-

4

-

4

-

2

-

1

-

1

-

392631

Anderson

The subunit structure of bovin ...

Bos taurus

Biochim. Biophys. Acta

635

194-199

1981

-

1

-

2

-

1

-

2

-

2

-

4

-

4

-

1

-

2

-

1

-

2

-

392632

Anderson

Immunochemical characterizatio ...

Bos taurus

J. Biol. Chem.

256

1888-1895

1981

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

392633

Blazyk

Temperature-dependent changes ...

Bos taurus

J. Biol. Chem.

256

691-694

1981

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

392654

Rydström

-

Mitochondrial nicotinamide nuc ...

Bos taurus

Mitochondria and Microsomes (Lee, C. P. , Schatz, G. , Dallner, G. eds. ) Addison-Wesley, Reading MA

317-335

1981

-

1

-

1

-

4

-

4

-

1

-

392634

O'Neal

The effect of metal ions on mi ...

Bos taurus

Biochim. Biophys. Acta

589

217-230

1980

-

1

13

-

1

-

1

-

1

-

1

-

4

1

-

4

-

1

-

13

1

-

1

-

1

-

1

-

392635

Rydström

Reconstitution of mitochondria ...

Bos taurus

Methods Enzymol.

55

811-816

1979

-

1

-

1

-

4

-

4

-

1

-

392636

Rydström

Assay of nicotinamide nucleoti ...

Azotobacter sp., Bos taurus, Escherichia coli, Mammalia

Methods Enzymol.

55

261-273

1979

-

4

-

2

-

6

-

16

-

16

-

2

-

6

-

392637

Höjeberg

Purification of mitochondrial ...

Bos taurus

Methods Enzymol.

55

275-283

1979

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

392638

Jacobs

Resolution and reconstitution ...

Rhodospirillum rubrum

Biochemistry

18

4315-4322

1979

-

2

-

1

-

1

-

4

-

4

-

2

-

1

-

392639

Hanson

The kinetic mechanism of pyrid ...

Escherichia coli

J. Biol. Chem.

254

888-893

1979

-

6

2

-

1

-

1

-

1

-

2

-

4

10

-

4

-

6

10

2

-

1

-

1

-

2

-

392640

Anderson

Purification and partial chara ...

Bos taurus

Arch. Biochem. Biophys.

187

180-190

1978

1

-

1

2

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

4

-

1

-

4

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

392641

Jacobs

Resolution and reconstitution ...

Rhodospirillum rubrum

Arch. Microbiol.

115

151-156

1977

1

-

2

-

1

-

1

-

1

-

2

-

4

-

1

-

4

-

2

-

1

-

1

-

2

-

392642

Höjeberg

Purification and molecular pro ...

Bos taurus

Biochem. Biophys. Res. Commun.

78

1183-1190

1977

-

1

-

2

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

2

-

1

-

1

-

1

-

392643

Rydström

Energy-linked nicotinamide nuc ...

Bos taurus, Escherichia coli, Rattus norvegicus, Rhodospirillum rubrum

Biochim. Biophys. Acta

463

155-184

1977

1

-

12

7

-

1

-

4

-

1

4

3

-

7

-

16

-

1

-

16

-

12

-

7

-

1

-

1

3

-

7

-

392644

O'Neal

Studies on sulfhydryl group mo ...

Bos taurus

J. Biol. Chem.

252

4552-4556

1977

-

1

-

1

-

1

-

1

-

4

-

4

-

1

-

1

-

1

-

392595

Rydström

-

Nicotinamide nucleotide transh ...

Bos taurus, Mammalia

The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )

13

51-88

1976

-

23

4

2

-

2

-

2

-

2

-

8

-

7

-

3

-

8

12

-

8

-

23

12

4

2

-

2

-

8

-

7

-

3

-

392645

Houghton

Dependence of Escherichia coli ...

Escherichia coli

Biochem. Biophys. Res. Commun.

73

751-757

1976

4

-

2

-

1

-

1

-

1

-

4

-

4

-

4

-

2

-

1

-

1

-

392646

Rydström

Evidence for a lipid dependenc ...

Bos taurus

Biochim. Biophys. Acta

430

419-425

1976

1

-

2

-

2

-

1

-

4

-

1

-

4

-

2

-

1

-

392647

Fisher

Resolution and reconstitution ...

Rhodospirillum rubrum

J. Biol. Chem.

250

819-825

1975

-

1

2

-

1

-

3

-

4

-

4

-

1

-

2

-

3

-

392583

Hoek

Comparative studies on nicotin ...

Escherichia coli

Biochim. Biophys. Acta

333

237-245

1974

-

1

-

1

-

2

-

4

-

4

-

1

-

2

-

392648

Singh

The pyridine-nucleotide transh ...

Salmonella enterica subsp. enterica serovar Typhimurium

J. Gen. Microbiol.

82

237-246

1974

-

1

-

4

-

4

-

392649

Berger

Purification and some properti ...

Rhodobacter sphaeroides

Arch. Biochem. Biophys.

159

25-31

1973

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

4

-

4

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

392650

Fisher

Studies on the mitochondrial e ...

Bos taurus

Biochemistry

12

1182-1188

1973

-

1

-

1

-

4

-

4

-

1

-

392651

Asano

Oxidative phosphorylation in M ...

Paracoccus denitrificans

Biochim. Biophys. Acta

143

477-486

1967

-

1

-

4

-

4

-

392655

Kaufman

Pyridine nucleotide transhydro ...

Bos taurus

J. Biol. Chem.

236

2133-2139

1961

-

1

-

4

1

-

1

-

4

-

4

-

1

-

4

-

1

-

Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle

Data extracted from this reference: