1.13.11.71: carotenoid-9',10'-cleaving dioxygenase

This is an abbreviated version!
For detailed information about carotenoid-9',10'-cleaving dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.71

Reaction

all-trans-beta-carotene
+
O2
=
all-trans-10'-apo-beta-carotenal
+
beta-ionone

Synonyms

BC-9',10'-oxygenase, Bcdo2, BCO2, beta,beta-carotene 9',10'-dioxygenase 2, beta,beta-carotene 9',10'-oxygenase, beta,beta-carotene-9',10'-dioxygenase, beta,beta-carotene-9,10-oxygenase 2, beta-carotene 9',10' oxygenase, beta-carotene 9',10'-oxygenase, beta-carotene-9',10'-oxygenase, beta-carotene-9,10'-oxygenase, CCD7, LjCCD7, ScBCO2, xanthophyll cleavage enzyme

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.71 carotenoid-9',10'-cleaving dioxygenase

Application

Application on EC 1.13.11.71 - carotenoid-9',10'-cleaving dioxygenase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
agriculture
a nonsense mutation c.196C>T in the beta-carotene oxygenase 2 gene is found to strongly associate with the yellow fat phenotype in sheep. The existence of individuals lacking this mutation, but still demonstrating yellow fat, suggests that additional mutations may cause a similar phenotype in this population. Animals homozygous for the mutation are not reported to suffer from any negative health or development traits, pointing towards a minor role of BCO2 in vitamin A formation
synthesis