1.13.11.71: carotenoid-9',10'-cleaving dioxygenase

This is an abbreviated version!
For detailed information about carotenoid-9',10'-cleaving dioxygenase, go to the full flat file.

Reaction

Synonyms

BC-9',10'-oxygenase, Bcdo2, BCO2, beta,beta-carotene 9',10'-dioxygenase 2, beta,beta-carotene 9',10'-oxygenase, beta,beta-carotene-9',10'-dioxygenase, beta,beta-carotene-9',10'-dioxygenase 2, beta,beta-carotene-9,10-oxygenase 2, beta-carotene 9',10' oxygenase, beta-carotene 9',10'-oxygenase, beta-carotene-9',10'-oxygenase, beta-carotene-9,10'-oxygenase, CCD1, CCD4b, CCD7, LjCCD7, ScBCO2, xanthophyll cleavage enzyme

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.71 carotenoid-9',10'-cleaving dioxygenase

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Results	in table
4	Activating Compound
21	AA Sequence
4	Application
8	Cloned(Commentary)
5	Disease/ Diagnostics
3	Expression
30	General Information
6	Inhibitors
4	kcat/KM [mM/s]
5	KM Value [mM]
9	Localization
5	Metals/Ions
26	Natural Substrates/ Products (Substrates)
14	Organic Solvent Stability
30	Organism
1	Pathway
6	pH Optimum
1	pH Range
6	Protein Variants
3	Purification (Commentary)
1	Reaction
29	Reference
66	Source Tissue
1	Specific Activity [micromol/min/mg]
50	Substrates and Products (Substrate)
2	Subunits
47	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
5	Temperature Stability [°C]
4	Turnover Number [1/s]

Disease

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Disease on EC 1.13.11.71 - carotenoid-9',10'-cleaving dioxygenase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Carcinogenesis

Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice.

25293877

Liver Diseases

Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice.

29266812

Non-alcoholic Fatty Liver Disease

Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice.

29266812

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