2.7.7.1: nicotinamide-nucleotide adenylyltransferase

This is an abbreviated version!
For detailed information about nicotinamide-nucleotide adenylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.1

2.7.7.1

degeneration

wallerian

neurodegenerative

neuroprotective

amaurosis

leber

nampt

self-destruct

axotomy

riboside

nadase

tiazofurin

axonopathies

pro-degenerative

analysis

drug development

pharmacology

medicine

Reaction

Synonyms

adenosine triphosphate-nicotinamide mononucleotide transadenylase, adenylyltransferase, nicotinamide mononucleotide, Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase, AtNMNAT, ATP:NMN adenylyltransferase, diphosphopyridine nucleotide pyrophosphorylase, Drosophila NMNAT, GlNMNAT, hNMNAT, hNMNAT-1, hNMNAT-2, human nicotinamide mononucleotide adenylyl-transferase, m-nonN-Nmnat1, mononucleotide adenylyltransferase, More, NAD synthase, NAD+ pyrophosphorylase, nadD, NadM-Nudix, NadR, NaMNAT, nicotinamide 5'-mononucleotide adenylyltransferase, nicotinamide 5'-mononucleotide adenylyltransferase-2, nicotinamide 5-mononucleotide adenylyltransferase-2, nicotinamide adenine dinucleotide pyrophosphorylase, nicotinamide mononucleotide adenylyl-transferase, nicotinamide mononucleotide adenylyltransferase, nicotinamide mononucleotide adenylyltransferase 1, nicotinamide mononucleotide adenylyltransferase 2, nicotinamide mononucleotide adenylyltransferase type 1, nicotinamide mononucleotide adenylyltransferase1, nicotinamide mononucleotide adenylyltransferase2, nicotinamide/nicotinate mononucleotide adenylyltransferase, nicotinamide/nicotinic acid mononucleotide adenylyltransferase, nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, nicotinate/nicotinamide mononucleotide adenyltransferase, NMN adenylyl transferase 1, NMN adenylyltransferase, NMN adenylyltransferase/ADP-ribose pyrophosphatase, NMN AT, NMN-adenylyltransferase, NMN/NaMN adenylyltransferase, NMN/NaMN adenylyltransferase 2, NMN/NaMN adenylyltransferase 3, NMNAT, NMNAT-2, NMNAT1, NMNAT2, NMNAT3, NMNATase, non-nuclear-localized-Nmnat1, PF3D7_1327600, PNAT, Pof1, pyridine nucleotide adenylyltransferase, Tc00.1047053507047.170, TK0067, TTHA1780, yNMNAT-1, yNMNAT-2

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.7 Nucleotidyltransferases

2.7.7.1 nicotinamide-nucleotide adenylyltransferase

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Results	in table
9	Activating Compound
8551	AA Sequence
10	Application
1	CAS Registry Number
39	Cloned(Commentary)
21	Crystallization (Commentary)
404	Disease/ Diagnostics
6	Expression
53	General Information
13	General Stability
11	IC50 Value
57	Inhibitors
27	kcat/KM [mM/s]
66	Ki Value [mM]
213	KM Value [mM]
51	Localization
86	Metals/Ions
60	Molecular Weight [Da]
87	Natural Substrates/ Products (Substrates)
368	Organism
6	Pathway
67	PDB ID
25	pH Optimum
2	pH Range
3	pH Stability
13	pI Value
12	Posttranslational Modification
42	Protein Variants
50	Purification (Commentary)
6	Reaction
11	Reaction Type
144	Reference
136	Source Tissue
31	Specific Activity [micromol/min/mg]
24	Storage Stability
297	Substrates and Products (Substrate)
61	Subunits
194	Synonyms
1	Systematic Name
19	Temperature Optimum [°C]
4	Temperature Range [°C]
20	Temperature Stability [°C]
57	Turnover Number [1/s]

KI Value

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KI Value on EC 2.7.7.1 - nicotinamide-nucleotide adenylyltransferase

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0.16 - 1

diphosphate

6 entries

0.023 - 0.502

NaAD+

6 entries

0.067 - 1.418

NAD+

6 entries

0.0315 - 0.089

P1-(adenosine-5')-P3-(nicotinamide-riboside-5')-triphosphate

6 entries

0.0328 - 0.3283

P1-(adenosine-5')-P3-(nicotinic-acid-riboside-5')-triphosphate

6 entries

0.0242 - 0.0736

P1-(adenosine-5')-P4-(nicotinamide-riboside-5')-tetraphosphate

6 entries

0.0217 - 0.6576

P1-(adenosine-5')-P4-(nicotinic-acid-riboside-5')-tetraphosphate

6 entries

0.0315 - 0.089

P1-(nicotinamide-riboside-5')-P3-(adenosine-5')-triphosphate

6 entries

0.0242 - 0.0736

P1-(nicotinamide-riboside-5')-P4-(adenosine-5')-tetraphosphate

6 entries

0.0217 - 0.6576

P1-(nicotinate-riboside-5')-P4-(adenosine-5')-tetraphosphate

12 entries