Reference on EC 2.7.7.1 - nicotinamide-nucleotide adenylyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dahmen, W.; Webb, B.; Preiss, J.
The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast
Arch. Biochem. Biophys.
120
440-450
1967
Escherichia coli, Escherichia coli B / ATCC 11303, Saccharomyces cerevisiae
Emanuelli, M.; Natalini, P.; Raffaelli, N.; Ruggieri, S.; Vita, A.; Magni, G.
NAD biosynthesis in human placenta: purification and characterization of homogeneous NMN adenylyltransferase
Arch. Biochem. Biophys.
298
29-34
1992
Homo sapiens
Sestini, S.; Ricci, C.; Micheli, V.; Pompucci, G.
Nicotinamide mononucleotide adenylyltransferase activity in human erythrocytes
Arch. Biochem. Biophys.
302
206-211
1993
Homo sapiens
Uhr, M.L.; Smulson, M.
NMN adenylyltransferase: its association with chromatin and with poly(ADP-ribose) polymerase
Eur. J. Biochem.
128
435-443
1982
Homo sapiens, Sus scrofa
Ting, H.H.; Whish, W.J.D.
A preliminary study of immobilized NAD pyrophosphorylase
Biochem. Soc. Trans.
8
635
1980
Sus scrofa
Atkinson, M.R.; Jackson, J.F.; Morton, R.K.
Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei: the effects of nicotine mononucleotide concentration and pH on dinucleotide synthesis
Biochem. J.
80
318-323
1961
Sus scrofa
Ferro, A.M.; Kuehl, L.
Adenosine triphosphate: nicotinamide mononucleotide adenylyltransferase of pig liver. Purification and properties
Biochim. Biophys. Acta
410
285-298
1975
Bos taurus, Rattus norvegicus, Sus scrofa
Lowe, G.; Tansley, G.
The stereochemical course of nucleotidyl transfer catalysed by NAD pyrophosphorylase
Eur. J. Biochem.
132
117-120
1983
Sus scrofa
Cantarow, W.; Stollar, B.D.
Nicotinamide mononucleotide adenylytransferase, a nonhistone chromatin protein. Purification and properties of the chicken erythrocyte enzyme
Arch. Biochem. Biophys.
180
26-34
1977
Anser sp., Gallus gallus, Gadidae, Frog, Meleagris gallopavo, pheasant
Ruggieri, S.; Gregori, L.; Natalini, P.; Vita, A.; Magni, G.
Recent observations on the structure and the properties of yeast NMN adenylyltransferase
Experientia
44
27-29
1988
Saccharomyces cerevisiae
Natalini, P.; Ruggieri, S.; Raffaelli, N.; Magni, G.
Nicotinamide mononucleotide adenylyltransferase. Molecular and enzymatic properties of the homogeneous enzyme from bakers yeast
Biochemistry
25
3725-3729
1986
Saccharomyces cerevisiae
Magni, G.; Natalini, P.; Santarelli, I.; Vita, A.; Raffaelli, N.; Ruggieri, S.
NAD pyrophosphorylase from yeast chromatin. Purification and properties
Basic Appl. Histochem.
31
255-271
1987
Saccharomyces cerevisiae
Natalini, P.; Santarelli, I.; Ruggieri, S.; Magni, G.
NMN adenylyltransferase from bakers' yeast: further properties
Ital. J. Biochem.
35
150A-152A
1986
Saccharomyces cerevisiae
-
Kono, M.; Shimizu, C.; Matsui, T.; Matsuura, F.
Purification of NAD pyrophosphorylase from muscle of skipjack and its properties
Nippon Suisan Gakkaishi
44
379-384
1978
Katsuwonus pelamis
-
Balducci, E.; Orsomando, G.; Polzonetti, V.; Vita, A.; Emanuelli, M.; Raffaelli, N.; Ruggieri, S.; Magni, G.; Natalini, P.
NMN adenylyltransferase from bull testis: purification and properties
Biochem. J.
310
395-400
1995
Bos taurus
Balducci, E.; Emanuelli, M.; Raffaelli, N.; Ruggieri, S.; Amici, A.; Magni, G.; Orsomando, G.; Polzonetti, V.; Natalini, P.
Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability
Anal. Biochem.
228
64-68
1995
Bos taurus
Raffaelli, N.; Sorci, L.; Amici, A.; Emanuelli, M.; Mazzola, F.; Magni, G.
Identification of a novel human nicotinamide mononucleotide adenylyltransferase
Biochem. Biophys. Res. Commun.
297
835-840
2002
Homo sapiens
Zhang, X.; Kurnasov, O.V.; Karthikeyan, S.; Grishin, N.V.; Osterman, A.L.; Zhang, H.
Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis
J. Biol. Chem.
278
13503-13511
2003
Homo sapiens
Garavaglia, S.; D'Angelo, I.; Emanuelli, M.; Carnevali, F.; Pierella, F.; Magni, G.; Rizzi, M.
Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis
J. Biol. Chem.
277
8524-8530
2002
Homo sapiens (Q9HAN9), Homo sapiens
Zhou, T.; Kurnasov, O.; Tomchick, D.R.; Binns, D.D.; Grishin, N.V.; Marquez, V.E.; Osterman, A.L.; Zhang, H.
Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin
J. Biol. Chem.
277
13148-13154
2002
Homo sapiens (Q9HAN9), Homo sapiens
Emanuelli, M.; Carnevali, F.; Saccucci, F.; Pierella, F.; Amici, A.; Raffaelli, N.; Magni, G.
Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase
J. Biol. Chem.
276
406-412
2001
Homo sapiens (Q9HAN9), Homo sapiens
Werner, E.; Ziegler, M.; Lerner, F.; Schweiger, M.; Heinemann, U.
Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN
FEBS Lett.
516
239-244
2002
Homo sapiens (Q9HAN9), Homo sapiens
Franchetti, P.; Cappellacci, L.; Pasqualini, M.; Grifantini, M.; Lorenzi, T.; Raffaelli, N.; Magni, G.
Dinucleoside polyphosphate NAD analogs as potential NMN adenylyltransferase inhibitors. Synthesis and biological evaluation
Nucleosides Nucleotides Nucleic Acids
22
865-868
2003
Saccharomyces cerevisiae, Homo sapiens, Methanocaldococcus jannaschii
Raffaelli, N.; Pisani, F.M.; Lorenzi, T.; Emanuelli, M.; Amici, A.; Ruggieri, S.; Magni, G.
Nicotinamide-mononucleotide adenylyltransferase from Methanococcus jannaschii
Methods Enzymol.
331
292-298
2001
Methanocaldococcus jannaschii, Saccharolobus solfataricus
Saridakis, V.; Christendat, D.; Kimber, M.S.; Dharamsi, A.; Edwards, A.M.; Pai, E.F.
Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes
J. Biol. Chem.
276
7225-7232
2001
Methanothermobacter thermautotrophicus
Saridakis, V.; Pai, E.F.
Mutational, structural, and kinetic studies of the ATP-binding site of Methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferase
J. Biol. Chem.
278
34356-34363
2003
Methanothermobacter thermautotrophicus
Boulton, S.; Kyle, S.; Durkacz, B.W.
Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: effects on NAD metabolism and DNA repair
Br. J. Cancer
76
845-851
1997
Mus musculus, Mus musculus L1210
Barile, M.; Passarella, S.; Danese, G.; Quagliariello, E.
Rat liver mitochondria can synthesize nicotinamide adenine dinucleotide from nicotinamide mononucleotide and ATP via a putative matrix nicotinamide mononucleotide adenylyltransferase
Biochem. Mol. Biol. Int.
38
297-306
1996
Rattus norvegicus
Emanuelli, M.; Carnevali, F.; Lorenzi, M.; Raffaelli, N.; Amici, A.; Ruggieri, S.; Magni, G.
Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzyme
FEBS Lett.
455
13-17
1999
Saccharomyces cerevisiae
Magni, G.; Raffaelli, N.; Emanuelli, M.; Amici, A.; Natalini, P.; Ruggieri, S.
Nicotinamide-mononucleotide adenylyltransferases from yeast and other microorganisms
Methods Enzymol.
280
248-255
1997
Saccharomyces cerevisiae, Saccharolobus solfataricus
Raffaelli, N.; Lorenzi, T.; Emanuelli, M.; Amici, A.; Ruggieri, S.; Magni, G.
Nicotinamide-mononucleotide adenylyltransferase from Sulfolobus solfataricus
Methods Enzymol.
331
281-292
2001
Saccharolobus solfataricus
Raffaelli, N.; Amici, A.; Emanuelli, M.; Ruggieri, S.; Magni, G.
Pyridine dinucleotide biosynthesis in archaebacteria: presence of NMN adenylyltransferase in Sulfolobus solfataricus
FEBS Lett.
355
233-236
1994
Saccharolobus solfataricus
Raffaelli, N.; Pisani, F.M.; Lorenzi, T.; Emanuelli, M.; Amici, A.; Ruggieri, S.; Magni, G.
Characterization of nicotinamide mononucleotide adenylyltransferase from thermophilic archaea
J. Bacteriol.
179
7718-7723
1997
Methanocaldococcus jannaschii, Saccharolobus solfataricus (P57084), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (P57084)
Yalowitz, J.A.; Jayaram, H.N.
Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase
Curr. Med. Chem.
9
749-758
2002
Saccharomyces cerevisiae, Homo sapiens, Mammalia, Mus musculus
Yalowitz, J.A.; Xiao, S.; Biju, M.P.; Antony, A.C.; Cummings, O.W.; Deeg, M.A.; Jayaram, H.N.
Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas
Biochem. J.
377
317-326
2004
Homo sapiens (Q9BZQ4), Homo sapiens
Magni, G.; Amici, A.; Emanuelli, M.; Orsomando, G.; Raffaelli, N.; Ruggieri, S.
Structure and function of nicotinamide mononucleotide adenylyltransferase
Curr. Med. Chem.
11
873-885
2004
Bacillus subtilis, Bos taurus, Saccharomyces cerevisiae, Haemophilus influenzae, Homo sapiens, Methanothermobacter thermautotrophicus, Methanocaldococcus jannaschii, Saccharolobus solfataricus
Berger, F.; Lau, C.; Dahlmann, M.; Ziegler, M.
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
J. Biol. Chem.
280
36334-36341
2005
Homo sapiens (Q96T66), Homo sapiens (Q9BZQ4), Homo sapiens (Q9HAN9), Homo sapiens
Sorci, L.; Cimadamore, F.; Scotti, S.; Petrelli, R.; Cappellacci, L.; Franchetti, P.; Orsomando, G.; Magni, G.
Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis
Biochemistry
46
4912-4922
2007
Homo sapiens (Q96T66), Homo sapiens (Q9BZQ4), Homo sapiens (Q9HAN9), Homo sapiens
Conforti, L.; Fang, G.; Beirowski, B.; Wang, M.S.; Sorci, L.; Asress, S.; Adalbert, R.; Silva, A.; Bridge, K.; Huang, X.P.; Magni, G.; Glass, J.D.; Coleman, M.P.
NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration
Cell Death Differ.
14
116-127
2007
Mus musculus
Sasaki, Y.; Araki, T.; Milbrandt, J.
Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy
J. Neurosci.
26
8484-8491
2006
Mus musculus (Q99JR6), Mus musculus (Q9EPA7)
Watanabe, M.; Tsukiyama, T.; Hatakeyama, S.
Protection of vincristine-induced neuropathy by WldS expression and the independence of the activity of Nmnat1
Neurosci. Lett.
411
228-232
2007
Mus musculus
Jia, H.; Yan, T.; Feng, Y.; Zeng, C.; Shi, X.; Zhai, Q.
Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axon-protective function
Neurosci. Lett.
413
46-51
2007
Mus musculus
Hashida, S.N.; Takahashi, H.; Kawai-Yamada, M.; Uchimiya, H.
Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase (AtNMNAT) is required for pollen tube growth
Plant J.
49
694-703
2007
Arabidopsis thaliana (F4K687), Arabidopsis thaliana
Zhai, R.G.; Cao, Y.; Hiesinger, P.R.; Zhou, Y.; Mehta, S.Q.; Schulze, K.L.; Verstreken, P.; Bellen, H.J.
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity
PLoS Biol.
4
2336-2348
2006
Drosophila melanogaster
-
Berger, F.; Lau, C.; Ziegler, M.
Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1
Proc. Natl. Acad. Sci. USA
104
3765-3770
2007
Escherichia coli, Homo sapiens
Huang, N.; Sorci, L.; Zhang, X.; Brautigam, C.A.; Li, X.; Raffaelli, N.; Magni, G.; Grishin, N.V.; Osterman, A.L.; Zhang, H.
Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism
Structure
16
196-209
2008
Synechocystis sp. (Q55928), Francisella tularensis (Q5NHR1)
Zhai, R.G.; Zhang, F.; Hiesinger, P.R.; Cao, Y.; Haueter, C.M.; Bellen, H.J.
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
Nature
452
887-891
2008
Drosophila melanogaster
Zhai, R.G.; Rizzi, M.; Garavaglia, S.
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme
Cell. Mol. Life Sci.
66
2805-2818
2009
Synechocystis sp., Bacillus anthracis, Escherichia coli, Haemophilus influenzae, Homo sapiens, Staphylococcus aureus, Pseudomonas aeruginosa, Methanothermobacter thermautotrophicus (O26253), Methanocaldococcus jannaschii (Q57961)
Lau, C.; Niere, M.; Ziegler, M.
The NMN/NaMN adenylyltransferase (NMNAT) protein family
Front. Biosci.
14
410-431
2009
Arabidopsis thaliana, Escherichia coli (P0A752), Saccharomyces cerevisiae (P53204), Homo sapiens (Q96T66), Homo sapiens
Yahata, N.; Yuasa, S.; Araki, T.
Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration
J. Neurosci.
29
6276-6284
2009
Mus musculus (Q99JR6), Mus musculus (Q9EPA7), Mus musculus
Zang, S.; Ali, Y.O.; Ruan, K.; Zhai, R.G.
Nicotinamide mononucleotide adenylyltransferase maintains active zone structure by stabilizing Bruchpilot
EMBO Rep.
14
87-94
2013
Drosophila melanogaster
Ali, Y.O.; Ruan, K.; Zhai, R.G.
NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy
Hum. Mol. Genet.
21
237-250
2012
Drosophila melanogaster
Lau, C.; Dolle, C.; Gossmann, T.; Agledal, L.; Niere, M.; Ziegler, M.
Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases
J. Biol. Chem.
285
18868-18876
2010
Homo sapiens (Q96T66), Homo sapiens (Q9BZQ4), Homo sapiens (Q9HAN9), Homo sapiens
Mayer, P.R.; Huang, N.; Dewey, C.M.; Dries, D.R.; Zhang, H.; Yu, G.
Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2
J. Biol. Chem.
285
40387-40396
2010
Mus musculus, Homo sapiens (Q9BZQ4)
Ali, Y.O.; McCormack, R.; Darr, A.; Zhai, R.G.
Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway
J. Biol. Chem.
286
19089-19099
2011
Drosophila melanogaster
Hashida, S.N.; Itami, T.; Takahashi, H.; Takahara, K.; Nagano, M.; Kawai-Yamada, M.; Shoji, K.; Goto, F.; Yoshihara, T.; Uchimiya, H.
Nicotinate/nicotinamide mononucleotide adenyltransferase-mediated regulation of NAD biosynthesis protects guard cells from reactive oxygen species in ABA-mediated stomatal movement in Arabidopsis
J. Exp. Bot.
61
3813-3825
2010
Arabidopsis thaliana
Raches, D.W.; Xiao, S.; Kusumanchi, P.; Yalowitz, J.; Sanghani, P.; Long, E.C.; Antony, A.C.; Jayaram, H.N.
Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5-mononucleotide adenylyltransferase-2
Med. Chem.
7
718-726
2011
Mus musculus
Hicks, A.N.; Lorenzetti, D.; Gilley, J.; Lu, B.; Andersson, K.E.; Miligan, C.; Overbeek, P.A.; Oppenheim, R.; Bishop, C.E.
Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo
PLoS ONE
7
e47869
2012
Mus musculus
Orsomando, G.; Cialabrini, L.; Amici, A.; Mazzola, F.; Ruggieri, S.; Conforti, L.; Janeckova, L.; Coleman, M.P.; Magni, G.
Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues
PLoS ONE
7
e53271
2012
Mus musculus (Q5HZI3), Mus musculus (Q99JR6), Mus musculus (Q9EPA7), Mus musculus
D'Angelo, I.; Raffaelli, N.; Dabusti, V.; Lorenzi, T.; Magni, G.; Rizzi, M.
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis
Structure
8
993-1004
2000
Methanocaldococcus jannaschii (Q57961), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q57961)
Pfoh, R.; Pai, E.F.; Saridakis, V.
Nicotinamide mononucleotide adenylyltransferase displays alternate binding modes for nicotinamide nucleotides
Acta Crystallogr. Sect. D
71
2032-2039
2015
Methanothermobacter thermautotrophicus (O26253), Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus ATCC 29096 (O26253)
Forero-Baena, N.; Sanchez-Lancheros, D.; Buitrago, J.; Bustos, V.; Ramirez-Hernandez, M.
Identification of a nicotinamide/nicotinate mononucleotide adenylyltransferase in Giardia lamblia (GlNMNAT)
Biochim. Open
1
61-69
2015
Giardia intestinalis (A8BIC5)
Kusumanchi, P.; Zhang, Y.; Jani, M.B.; Jayaram, N.H.; Khan, R.A.; Tang, Y.; Antony, A.C.; Jayaram, H.N.
Nicotinamide mononucleotide adenylyltransferase2 overexpression enhances colorectal cancer cell-kill by Tiazofurin
Cancer Gene Ther.
20
403-412
2013
Homo sapiens (Q9BZQ4)
Pan, L.Z.; Ahn, D.G.; Sharif, T.; Clements, D.; Gujar, S.A.; Lee, P.W.
The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target
Cell Cycle
13
1041-1048
2014
Homo sapiens (Q9BZQ4), Homo sapiens
Mao, X.R.; Kaufman, D.M.; Crowder, C.M.
Nicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response
Cell Death Dis.
7
e2113
2016
Mus musculus (Q9EPA7), Mus musculus
Song, T.; Yang, L.; Kabra, N.; Chen, L.; Koomen, J.; Haura, E.B.; Chen, J.
The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription
J. Biol. Chem.
288
20908-20917
2013
Homo sapiens (Q9HAN9), Homo sapiens
Kato, M.; Lin, S.J.
YCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in Saccharomyces cerevisiae
J. Biol. Chem.
289
15577-15587
2014
Saccharomyces cerevisiae (P25576), Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4742 (P25576)
Nino, C.H.; Forero-Baena, N.; Contreras, L.E.; Sanchez-Lancheros, D.; Figarella, K.; Ramirez, M.H.
Identification of the nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi
Mem. Inst. Oswaldo Cruz
110
890-897
2015
Trypanosoma cruzi (Q4DPR9), Trypanosoma cruzi, Trypanosoma cruzi CL Brener (Q4DPR9)
Liang, J.; Wang, P.; Wei, J.; Bao, C.; Han, D.
Nicotinamide mononucleotide adenylyltransferase 1 protects neural cells against ischemic injury in primary cultured neuronal cells and mouse brain with ischemic stroke through AMP-activated protein kinase activation
Neurochem. Res.
40
1102-1110
2015
Mus musculus (Q9EPA7), Mus musculus
Contreras, L.E.; Neme, R.; Ramirez, M.H.
Identification and functional evaluation of Leishmania braziliensis nicotinamide mononucleotide adenylyltransferase
Protein Expr. Purif.
115
26-33
2015
Leishmania braziliensis (A4H990), Leishmania braziliensis
Sakuraba, H.; Kanai, K.; Goda, S.; Kawarabayasi, Y.; Ohshima, T.
A nicotinamide mononucleotide adenylyltransferase with unique adenylyl group donor specificity from a hyperthermophilic archaeon, Pyrococcus horikoshii OT-3
J. Mol. Catal. B
23
273-279
2003
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
-
Lavado-Roldan, A.; Fernandez-Chacon, R.
Two for the price of one a neuroprotective chaperone kit within NAD synthase protein NMNAT2
PLoS Biol.
14
e1002522
2016
Homo sapiens (Q9BZQ4)
Hachisuka, S.I.; Sato, T.; Atomi, H.
Hyperthermophilic archaeon Thermococcus kodakarensis utilizes a four-step pathway for NAD+ salvage through nicotinamide deamination
J. Bacteriol.
200
e00785-17
2018
Thermococcus kodakarensis (Q5JEF8), Thermococcus kodakarensis ATCC BAA-918 (Q5JEF8)
Wang, X.; Zhou, Y.; Wang, L.; Liu, W.; Liu, Y.; Peng, C.; Zhao, Z.
Engineering Escherichia coli nicotinic acid mononucleotide adenylyltransferase for fully active amidated NAD biosynthesis
Appl. Environ. Microbiol.
83
e00692
2017
Escherichia coli (A0A140NE60), Escherichia coli BL21-DE3 (A0A140NE60)
Wang, S.; Han, J.; Xia, J.; Hu, Y.; Shi, L.; Ren, A.; Zhu, J.; Zhao, M.
Overexpression of nicotinamide mononucleotide adenylyltransferase (nmnat) increases the growth rate, Ca2+ concentration and cellulase production in Ganoderma lucidum
Appl. Microbiol. Biotechnol.
104
7079-7091
2020
Ganoderma lucidum (A0A3Q8R3X7), Ganoderma lucidum
Rossi, F.; Geiszler, P.C.; Meng, W.; Barron, M.R.; Prior, M.; Herd-Smith, A.; Loreto, A.; Lopez, M.Y.; Faas, H.; Pardon, M.C.; Conforti, L.
NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy
Behav. Brain Res.
339
140-152
2018
Mus musculus (Q9EPA7), Mus musculus
Ma, X.; Zhu, Y.; Lu, J.; Xie, J.; Li, C.; Shin, W.; Qiang, J.; Liu, J.; Dou, S.; Xiao, Y.; Wang, C.; Jia, C.; Long, H.; Yang, J.; Fang, Y.; Jiang, L.; Zhang, Y.; Zhang, S.; Zhai, R.; Liu, C.; Li, D.
Nicotinamide mononucleotide adenylyl transferase uses its NAD+ substrate-binding site to chaperone phosphorylated TAU
eLife
9
e51859
2020
Mus musculus (Q99JR6), Drosophila melanogaster (Q9VC03)
Yue, Z.; Ma, Y.; You, J.; Li, Z.; Ding, Y.; He, P.; Lu, X.; Jiang, J.; Chen, S.; Liu, P.
NMNAT3 is involved in the protective effect of SIRT3 in Ang II-induced cardiac hypertrophy
Exp. Cell Res.
347
261-273
2016
Mus musculus (Q99JR6)
Lukacs, M.; Gilley, J.; Zhu, Y.; Orsomando, G.; Angeletti, C.; Liu, J.; Yang, X.; Park, J.; Hopkin, R.J.; Coleman, M.P.; Zhai, R.G.; Stottmann, R.W.
Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence
Exp. Neurol.
320
112961
2019
Homo sapiens (Q9BZQ4), Homo sapiens
Contreras Rodriguez, L.E.; Ziegler, M.; Ramirez Hernandez, M.H.
Kinetic and oligomeric study of Leishmania braziliensis nicotinate/nicotinamide mononucleotide adenylyltransferase
Heliyon
6
e03733
2020
Leishmania braziliensis
Konishi, K.; Ueda, S.; Kawano, M.; Osawa, S.; Tamura, T.; Hokazono, E.; Kayamori, Y.; Sakasegawa, S.I.
Characterization and application of a novel nicotinamide mononucleotide adenylyltransferase from Thermus thermophilus HB8
J. Biosci. Bioeng.
125
385-389
2018
Thermus thermophilus (Q5SHF0)
Bathke, J.; Fritz-Wolf, K.; Brandstaedter, C.; Burkhardt, A.; Jortzik, E.; Rahlfs, S.; Becker, K.
Structural and functional characterization of Plasmodium falciparum nicotinic acid nononucleotide adenylyltransferase
J. Mol. Biol.
428
4946-4961
2016
Plasmodium falciparum (Q8IE38), Plasmodium falciparum
Eren, G.
Homology modeling of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Insights into isoenzyme-specific differences using molecular docking simulatons
Lett. Drug Des. Discov.
14
727-736
2017
Homo sapiens (Q9BZQ4)
-
Sanchez-Lancheros, D.M.; Ospina-Giraldo, L.F.; Ramirez-Hernandez, M.H.
Nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi (TcNMNAT) a cytosol protein target for serine kinases
Mem. Inst. Oswaldo Cruz
111
670-675
2016
Trypanosoma cruzi, Trypanosoma cruzi CL Brener
Pottorf, T.; Mann, A.; Fross, S.; Mansel, C.; Vohra, B.P.S.
Nicotinamide mononucleotide adenylyltransferase 2 maintains neuronal structural integrity through the maintenance of golgi structure
Neurochem. Int.
121
86-97
2018
Mus musculus (Q8BNJ3)
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