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2.7.1.77: nucleoside phosphotransferase

This is an abbreviated version!
For detailed information about nucleoside phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.77

Reaction

A nucleotide
+
a 2'-deoxyribonucleoside
=
a nucleoside
 +
a 2'-deoxyribonucleoside 5'-phosphate

Synonyms

nonspecific nucleoside phosphotransferase, NPT, nucleotide:3'-deoxynucleoside 5'-phosphotransferase, phosphotransferase, nucleoside

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.77 nucleoside phosphotransferase

Inhibitors

Inhibitors on EC 2.7.1.77 - nucleoside phosphotransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,4-dinitrofluorobenzene
-
-
AgCl
-
1 mM, 91% inhibition
arsenate
-
strong competitive inhibitor
cAMP
-
strong competitive inhibitor
Cd2+
-
2 mM, at least 80% inhibition of transphosphorylation
CuSO4
-
1 mM, 23% inhibition
cysteine
glutathione
iodoacetate
-
1 mM, 41% inhibition
NaF
-
0.25 M, phosphatase is inhibited by less than 10%
PCMB
-
1 mM, 17% inhibition
phosphate
-
competitive inhibitor of the associated enzyme form
Urea
-
6 M, complete inactivation
uridine
-
inhibitor of phosphatase reaction