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2.7.1.36: mevalonate kinase

This is an abbreviated version!
For detailed information about mevalonate kinase, go to the full flat file.

Word Map on EC 2.7.1.36

Reaction

ATP
+
(R)-mevalonate
=
ADP
 +
(R)-5-phosphomevalonate

Synonyms

ATP: mevalonate 5-phosphotransferase, ATP:mevalonate 5-phosphotransferase, GbMVK, kinase, mevalonate (phosphorylating), mevalonate 5-phosphotransferase, mevalonate phosphokinase, mevalonic acid kinase, mevalonic kinase, MmMK, MVA kinase, MVK, SSO0383, TcMVK, TeMVK

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.36 mevalonate kinase

pH Range

pH Range on EC 2.7.1.36 - mevalonate kinase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 10
-
approx. 10% of maximal activity at pH 5.0, approx. 90% of maximal activity at pH 10.0
5 - 7
-
at least 60% of maximal activity between pH 5.0 and 7.0
5 - 9
-
more than 50% of maximal activity at pH 5.0 and pH 9.0
5.5 - 9
-
approx. 30% of maximal activity at pH 5.5, approx. 60% of maximal activity at pH 9
6 - 9
6.5 - 9
-
approx. 40% of maximal activity at pH 6.5, approx. 70% of maximal activity at pH 9.0
6.5 - 9.5
more than 50% activity between pH 6.5 and 9.5