Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.0324 - 2.16
(R)-mevalonate
0.035 - 2.88
(R,S)-mevalonate
0.024 - 0.167
(R,S)mevalonate
0.27
(RS)-mevalonate
-
pH 7.0, 25°C
0.019 - 0.27
(RS)mevalonate
0.6
Ca-adenosine 5'-O-(2-thio-(R)-triphosphate)
-
pH 8.0
0.14
Ca-adenosine 5'-O-(2-thio-(S)-triphosphate)
-
pH 8.0
0.22
Cd-adenosine 5'-O-(1-thio-(R)-triphosphate)
-
pH 8.0
0.28
Cd-adenosine 5'-O-(1-thio-(S)-triphosphate)
-
pH 8.0
0.059
Cd-adenosine 5'-O-(2-thio-(R)-triphosphate)
-
pH 8.0
0.46
Cd-adenosine 5'-O-(2-thio-(S)-triphosphate)
-
pH 8.0
0.09
Co-adenosine 5'-O-(1-thio-(R)-triphosphate)
-
pH 8.0
0.2
Co-adenosine 5'-O-(1-thio-(S)-triphosphate)
-
pH 8.0
0.05
Co-adenosine 5'-O-(2-thio-(R)-triphosphate)
-
pH 8.0
0.1
Co-adenosine 5'-O-(2-thio-(S)-triphosphate)
-
pH 8.0
2.44
Mg-adenosine 5'-O-(1-thio-(R)-triphosphate)
-
pH 8.0
0.16
Mg-adenosine 5'-O-(1-thio-(S)-triphosphate)
-
pH 8.0
0.59
Mg-adenosine 5'-O-(2-thio-(R)-triphosphate)
-
pH 8.0
0.12
Mg-adenosine 5'-O-(2-thio-(S)-triphosphate)
-
pH 8.0
0.29
Mn-adenosine 5'-O-(2-thio-(R)-triphosphate)
-
pH 8.0
0.075
Mn-adenosine 5'-O-(2-thio-(S)-triphosphate)
-
pH 8.0
0.091
Ni-adenosine 5'-O-(2-thio-(R)-triphosphate)
-
pH 8.0
0.14
Ni-adenosine 5'-O-(2-thio-(S)-triphosphate)
-
pH 8.0
0.041
R,S-mevalonate
-
pH 7.5, 30°C
0.0426 - 0.046
RS-mevalonate
0.12
Zn-adenosine 5'-O-(2-thio-(R)-triphosphate)
-
pH 8.0
0.058
Zn-adenosine 5'-O-(2-thio-(S)-triphosphate)
-
pH 8.0
additional information
additional information
-
Michaelis-Menten kinetics
-
0.0324
(R)-mevalonate
mutant T104A, 30°C, pH 7.5
0.035
(R)-mevalonate
-
native enzyme, pH 7.5, 25°C
0.035
(R)-mevalonate
-
wild-type, pH 7.5, 34°C
0.0408
(R)-mevalonate
wild-type, 30°C, pH 7.5
0.0459
(R)-mevalonate
mutant R388X, 30°C, pH 7.5
0.0473
(R)-mevalonate
mutant L54A, 30°C, pH 7.5
0.061
(R)-mevalonate
-
mutant C281S, pH 7.5, 34°C
0.068
(R)-mevalonate
-
apparent value, in 50 mM Tris, 50 mM NaCl (pH 7.6), at 30°C
0.07
(R)-mevalonate
-
mutant C107A, pH 7.5, 34°C
0.071
(R)-mevalonate
-
mutant C107A/C281A, pH 7.5, 34°C
0.0745
(R)-mevalonate
mutant T104A/I196A, 30°C, pH 7.5
0.076
(R)-mevalonate
-
mutant C107S, pH 7.5, 34°C
0.09
(R)-mevalonate
-
at pH 7.5, temperature not specified in the publication
0.106
(R)-mevalonate
-
mutant C281A, pH 7.5, 34°C
0.106
(R)-mevalonate
-
wild-type, pH 7.5, 34°C
0.111
(R)-mevalonate
-
mutant C107S/C281S, pH 7.5, 34°C
0.1163
(R)-mevalonate
mutant I196A, 30°C, pH 7.5
0.186
(R)-mevalonate
-
mutant A141C, pH 7.5, 34°C
0.228
(R)-mevalonate
mutant I56A, 30°C, pH 7.5
0.323
(R)-mevalonate
mutant Y149A, 30°C, pH 7.5
0.33
(R)-mevalonate
-
pH 10, 37°C
0.3319
(R)-mevalonate
at pH 7.0 and 30°C
0.4591
(R)-mevalonate
mutant T104A/I196A/R388X, 30°C, pH 7.5
0.616
(R)-mevalonate
-
H20L mutant enzyme, pH 7.5, 25°C
2.16
(R)-mevalonate
-
H20Y mutant enzyme, pH 7.5, 25°C
0.035
(R,S)-mevalonate
-
pH 7.5, 25°C, recombinant mevalonate kinase
0.069
(R,S)-mevalonate
-
pH 8.0, 70°C, recombinant mevalonate kinase
0.15
(R,S)-mevalonate
-
pH 7.0, 25°C, recombinant mevalonate kinase
0.288
(R,S)-mevalonate
-
pH 7.0, 30°C
2.88
(R,S)-mevalonate
-
pH 7.0, 30°C, K13M mutant mevalonate kinase
0.024
(R,S)mevalonate
-
-
0.167
(R,S)mevalonate
-
V377I mutant mevalonate kinase
0.019
(RS)mevalonate
-
liver mevalonate kinase
0.069
(RS)mevalonate
-
recombinant mevalonate kinase
0.27
(RS)mevalonate
liver mevalonate kinase
0.025
ATP
-
mutant D204A, pH 7.0, 30°C
0.0403
ATP
mutant T104A, 30°C, pH 7.5
0.066
ATP
-
mutant D204N, pH 7.0, 30°C
0.074
ATP
-
wild-type, pH 7.0, 30°C
0.092
ATP
-
pH 8.0, 70°C, recombinant mevalonate kinase
0.092
ATP
-
recombinant mevalonate kinase
0.1
ATP
-
V377I mutant mevalonate kinase
0.113
ATP
-
mutant E19D, pH 7.0, 30°C
0.131
ATP
-
mutant E296Q, pH 7.0, 30°C
0.14
ATP
-
at pH 7.5, temperature not specified in the publication
0.1474
ATP
at pH 7.0 and 30°C
0.15
ATP
-
pH 7.5, 30°C, recombinant S145A mutant mevalonate kinase
0.166
ATP
-
pH 7.0, 30°C, K13M mevalonate kinase
0.1784
ATP
wild-type, 30°C, pH 7.5
0.2321
ATP
mutant L54A, 30°C, pH 7.5
0.3
ATP
-
liver mevalonate kinase
0.3018
ATP
mutant I196A, 30°C, pH 7.5
0.3077
ATP
mutant T104A/I196A, 30°C, pH 7.5
0.38
ATP
-
pH 7.5, 30°C, recombinant T243A mevalonate kinase
0.3954
ATP
mutant T104A/I196A/R388X, 30°C, pH 7.5
0.41
ATP
-
pH 7.5, 30°C, recombinant S146A mevalonate kinase
0.44
ATP
-
pH 7.0, 25°C, recombinant mevalonate kinase
0.464
ATP
-
apparent value, in 50 mM Tris, 50 mM NaCl (pH 7.6), at 30°C
0.51
ATP
-
pH 7.5, 30°C, recombinant S201A mevalonate kinase
0.614
ATP
mutant R388X, 30°C, pH 7.5
0.68
ATP
-
pH 6.5, 30°C, at 1 mM Mg2+
0.68
ATP
-
ATP in form of MgATP2-
0.6896
ATP
mutant Y149A, 30°C, pH 7.5
0.8097
ATP
mutant I56A, 30°C, pH 7.5
0.95
ATP
-
pH 7.5, 25°C, recombinant mevalonate kinase
0.95
ATP
-
wild-type, pH 7.5, 34°C
0.953
ATP
-
native enzyme, pH 7.5, 25°C
0.97
ATP
-
mutant A141C, pH 7.5, 34°C
1.18
ATP
-
wild-type, pH 7.5, 34°C
1.22
ATP
-
pH 7.5, 34°C, K272R mutant mevalonate kinase
1.54
ATP
-
pH 7.0, 30°C, enzyme from etiolated cotyledons
1.54
ATP
-
pH 7.5, 34°C, R196L mutant mevalonate kinase
1.56
ATP
-
mutant E193Q, pH 7.0, 30°C
1.58
ATP
-
mutant C107A/C281A, pH 7.5, 34°C
1.75
ATP
-
pH 7.0, 30°C, enzyme fom green leaves
1.75
ATP
liver mevalonate kinase
1.75
ATP
-
ATP in form of MgATP2-
1.81
ATP
-
H20L mutant enzyme, pH 7.5, 25°C
2.61
ATP
-
mutant C107A, pH 7.5, 34°C
2.7
ATP
-
H20Y mutant enzyme enzyme, pH 7.5, 25°C
2.76
ATP
-
mutant C281A, pH 7.5, 34°C
2.95
ATP
-
pH 7.5, 34°C, K272A mutant mevalonate kinase
2.97
ATP
-
mutant C281S, pH 7.5, 34°C
2.98
ATP
-
pH 7.5, 34°C, R196Q mutant mevalonate kinase
3
ATP
-
pH 7.5, 34°C, R196V mutant mevalonate kinase
3.11
ATP
-
mutant C107S, pH 7.5, 34°C
3.36
ATP
-
mutant C107S/C281S, pH 7.5, 34°C
0.13
DL-mevalonate
-
pH 7.5, 30°C
5.1
DL-mevalonate
-
pH 7.0, 35°C
0.012
mevalonate
-
mutant D204N, pH 7.0, 30°C
0.024
mevalonate
-
wild-type, pH 7.0, 30°C
0.05
mevalonate
-
pH 7.9, 37°C
0.052
mevalonate
-
mutant E19D, pH 7.0, 30°C
0.076
mevalonate
-
pH 7.5, 30°C
0.08
mevalonate
-
pH 7.9, 37°C
0.11
mevalonate
-
pH 7.5, 34°C
0.11
mevalonate
-
mutant E296Q, pH 7.0, 30°C
0.2
mevalonate
-
mutant D204A, pH 7.0, 30°C
0.25
mevalonate
-
pH 7.5, 34°C, K272R mutant mevalonate kinase
0.253
mevalonate
-
pH 7.5, 30°C, recombinant S145A mevalonate kinase
0.47
mevalonate
-
pH 7.5, 30°C, recombinant T243A mevalonate kinase
0.51
mevalonate
-
pH 7.5, 30°C, recombinant S146A mevalonate kinase
0.51
mevalonate
-
pH 7.5, 34°C, K272A mutant mevalonate kinase
1.02
mevalonate
-
mutant E193Q, pH 7.0, 30°C
1.43
mevalonate
-
pH 7.5, 34°C, R196L mutant mevalonate kinase
2.5
mevalonate
-
pH 7.5, 30°C, recombinant S201A mevalonate kinase
4.03
mevalonate
-
pH 7.5, 34°C, R196V mutant mevalonate kinase
9.28
mevalonate
-
pH 7.5, 34°C, R196Q mutant mevalonate kinase
0.0426
RS-mevalonate
-
pH 7.0, 30°C, enzyme from etiolated cotyledons
0.046
RS-mevalonate
-
pH 7.0, 30°C, leaf enzyme
2.7.1.36 mevalonate kinase
results (
results (
top
