2.7.1.173: nicotinate riboside kinase

This is an abbreviated version!
For detailed information about nicotinate riboside kinase, go to the full flat file.

Reaction

Synonyms

More, NaR kinase, nicotinamide riboside kinase, nicotinamide riboside kinase 1, nicotinamide riboside kinase 2, nicotinic acid riboside kinase, nicotinic acid riboside kinase 1, NMRK1, NMRK2, NR kinase, Nrk, NRK1, Nrk2, ribosylnicotinic acid kinase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.173 nicotinate riboside kinase

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Results	in table
12	AA Sequence
1	Application
6	Cloned(Commentary)
8	Cofactor
2	Crystallization (Commentary)
1	Expression
16	General Information
14	kcat/KM [mM/s]
14	KM Value [mM]
5	Metals/Ions
9	Natural Substrates/ Products (Substrates)
9	Organism
3	Pathway
1	PDB ID
3	pH Optimum
6	Protein Variants
4	Purification (Commentary)
2	Reaction
8	Reference
13	Source Tissue
1	Specific Activity [micromol/min/mg]
26	Substrates and Products (Substrate)
2	Subunits
27	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
14	Turnover Number [1/s]

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Reference on EC 2.7.1.173 - nicotinate riboside kinase

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REF.

AUTHORS

TITLE

JOURNAL

VOL.

PAGES

YEAR

ORGANISM (UNIPROT)

PUBMED ID

SOURCE

682879

Khan, J.A.; Xiang, S.; Tong, L.

Crystal structure of human nicotinamide riboside kinase

Structure

15

1005-1013

2007

Homo sapiens (Q9NWW6)

17698003

brenda

698901

Belenky, P.; Christensen, K.C.; Gazzaniga, F.; Pletnev, A.A.; Brenner, C.

Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism

J. Biol. Chem.

284

158-164

2009

Saccharomyces cerevisiae

19001417

brenda

718225

Matsui, A.; Ashihara, H.

Nicotinate riboside salvage in plants: presence of nicotinate riboside kinase in mungbean seedlings

Plant Physiol. Biochem.

46

104-108

2008

Vigna radiata var. radiata

18042392

brenda

718250

Tempel, W.; Rabeh, W.M.; Bogan, K.L.; Belenky, P.; Wojcik, M.; Seidle, H.F.; Nedyalkova, L.; Yang, T.; Sauve, A.A.; Park, H.W.; Brenner, C.

Nicotinamide riboside kinase structures reveal new pathways to NAD+

PLoS Biol.

5

e263

2007

Homo sapiens (Q9NPI5), Homo sapiens (Q9NWW6)

17914902

brenda

738213

Zamporlini, F.; Ruggieri, S.; Mazzola, F.; Amici, A.; Orsomando, G.; Raffaelli, N.

Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD+ biosynthetic machinery in mammalian cells

FEBS J.

281

5104-5119

2014

Homo sapiens

25223558

brenda

739212

Sociali, G.; Raffaghello, L.; Magnone, M.; Zamporlini, F.; Emionite, E.; Sturla, L.; Bianchi, G.; Vigliarolo, T.; Nahimana, A.; Nencioni, A.; Raffaelli, N.; Bruzzone, S

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

Oncotarget

7

2968-2984

2016

Homo sapiens (Q9NWW6)

26658104

brenda

761705

Fletcher, R.S.; Lavery, G.G.

The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolism

J. Mol. Endocrinol.

61

R107-R121

2018

Homo sapiens (Q9NPI5), Homo sapiens (Q9NWW6)

30307159

brenda

Entries 1 - 20 of 7

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