Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.173 extracted from

  • Sociali, G.; Raffaghello, L.; Magnone, M.; Zamporlini, F.; Emionite, E.; Sturla, L.; Bianchi, G.; Vigliarolo, T.; Nahimana, A.; Nencioni, A.; Raffaelli, N.; Bruzzone, S
    Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model (2016), Oncotarget, 7, 2968-2984.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene NRK1, quantitative real-time PCR enzyme expression analysis Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information enzyme NRK1 specific silencing in human ovarian carcinoma cell line OVCAR-3 by NRK1-specific siRNA Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the main NRK activity in human OVCAR-3 cells is due to the expression of enzyme NRK1 ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NWW6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ovarian carcinoma cell
-
Homo sapiens
-
OVCAR-3 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the main NRK activity in human OVCAR-3 cells is due to the expression of enzyme NRK1 Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
nicotinic acid riboside kinase 1
-
Homo sapiens
NRK1
-
Homo sapiens

General Information

General Information Comment Organism
malfunction in NRK1-silenced cells, both nicotinamide riboside- and NMN-mediated rescue from FK866-induced NAD+ depletion and cell death are potently and significantly reduced, overview Homo sapiens