2.4.1.223: glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.223

2.4.1.223

heparan

proteoglycans

glycosyltransferases

ext-like

glycosaminoglycans

extls

chondroitin

exostosins

mucous

n-acetylgalactosamine

tetrasaccharide

wingless

decapentaplegic

brunner

heparitinase

pancreaticobiliary

hspgs

fam20b

Reaction

[protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine

[protein]-3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine

Synonyms

alpha-N-acetylglucosaminyltransferase I, alpha1,4-N-acetylglucosaminyltransferase, botv, brother of tout-velu, Exostosin-like 2, EXTL2, EXTL3, Galntl-1, glucuronosylgalactosylproteoglycan 4-alpha-N-acetylglucosaminyltransferase, N-acetylgalactosaminyltransferase-like 1

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.223 glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

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37	AA Sequence
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2	General Information
1	Inhibitors
3	Localization
4	Natural Substrates/ Products (Substrates)
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Natural Substrates Products

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Natural Substrates Products on EC 2.4.1.223 - glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

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UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1-3)-beta-D-galactosyl-(1-3)-beta-D-galactosyl-(1-4)-beta-D-xylosyl-proteoglycan

UDP + alpha-N-acetyl-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-beta-D-galactosyl-(1-3)-beta-D-galactosyl-(1-4)-beta-D-xylosyl-proteoglycan

3 entries

additional information

Xenopus laevis

Q6PA81

N-acetylgalactosaminyltransferase-like 1 specifically interferes with the activity of TGF-beta type II receptor ActR-IIB in vivo

686299