2.3.3.8: ATP citrate synthase

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For detailed information about ATP citrate synthase, go to the full flat file.

Reaction

Synonyms

ACL, ACL1, ACL2, ACLA, ACLB, ACLY, adenosine triphosphate citrate lyase, ATP citrate (pro-S)-lyase, ATP citrate lyase, ATP citrate lyase isoform 2, ATP-citrate lyase, ATP-citrate synthase A-2, ATP-citrate synthase alpha chain protein 2, ATP-citric lyase, ATP:citrate lyase, ATP:citrate oxaloacetate lyase ((pro-3S)-CH2COO--> acetyl-CoA) (ATP-dephosphorylating), ATP:citrate oxaloacetate-lyase (pro-3S-CH2COO->acetyl-CoA, ATP dephosphorylating), ATP:citrate oxaloacetate-lyase CoA-acetylating and ATP-dephosphorylating, Citrate cleavage enzyme, citrate-ATP lyase, citric cleavage enzyme, Earlier Degraded Tapetum1, EC 4.1.3.8, EDT1, Os11g0696200

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.3 Acyl groups converted into alkyl groups on transfer

                2.3.3.8 ATP citrate synthase

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Results	in table
16	Activating Compound
7726	AA Sequence
12	Application
1	CAS Registry Number
23	Cloned(Commentary)
7	Crystallization (Commentary)
446	Disease/ Diagnostics
20	Expression
53	General Information
6	General Stability
18	IC50 Value
123	Inhibitors
3	kcat/KM [mM/s]
7	Ki Value [mM]
57	KM Value [mM]
49	Localization
20	Metals/Ions
50	Molecular Weight [Da]
56	Natural Substrates/ Products (Substrates)
174	Organism
2	Oxidation Stability
9	Pathway
98	PDB ID
11	pH Optimum
4	pH Range
2	pH Stability
1	pI Value
26	Posttranslational Modification
9	Protein Variants
38	Purification (Commentary)
8	Reaction
1	Reaction Type
155	Reference
132	Source Tissue
20	Specific Activity [micromol/min/mg]
6	Storage Stability
153	Substrates and Products (Substrate)
37	Subunits
132	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]

pH Range

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pH Range on EC 2.3.3.8 - ATP citrate synthase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

6 - 8.5

Chlorobium limicola

Q9AQH6

more than 80% of maximum activity within this range

658601

6.9 - 8.3

Ricinus communis

-

pH 6.9: about 45% of maximal activity, pH 8.3: about 50% of maximal activity

488198

7 - 8.8

Talaromyces trachyspermus

-

about 50% of maximal activity at pH 7.0 and at pH 8.8

488203

7.3 - 9.5

Lipomyces starkeyi

-

about 50% of maximal activity at pH 7.3 and at pH 9.5

488187