2.3.3.8: ATP citrate synthase

This is an abbreviated version!
For detailed information about ATP citrate synthase, go to the full flat file.

Reaction

Synonyms

ACL, ACL1, ACL2, ACLA, ACLB, ACLY, adenosine triphosphate citrate lyase, ATP citrate (pro-S)-lyase, ATP citrate lyase, ATP citrate lyase isoform 2, ATP-citrate lyase, ATP-citrate synthase A-2, ATP-citrate synthase alpha chain protein 2, ATP-citric lyase, ATP:citrate lyase, ATP:citrate oxaloacetate lyase ((pro-3S)-CH2COO--> acetyl-CoA) (ATP-dephosphorylating), ATP:citrate oxaloacetate-lyase (pro-3S-CH2COO->acetyl-CoA, ATP dephosphorylating), ATP:citrate oxaloacetate-lyase CoA-acetylating and ATP-dephosphorylating, Citrate cleavage enzyme, citrate-ATP lyase, citric cleavage enzyme, Earlier Degraded Tapetum1, EC 4.1.3.8, EDT1, Os11g0696200

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.3 Acyl groups converted into alkyl groups on transfer

                2.3.3.8 ATP citrate synthase

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Results	in table
16	Activating Compound
7726	AA Sequence
12	Application
1	CAS Registry Number
23	Cloned(Commentary)
7	Crystallization (Commentary)
446	Disease/ Diagnostics
20	Expression
53	General Information
6	General Stability
18	IC50 Value
123	Inhibitors
3	kcat/KM [mM/s]
7	Ki Value [mM]
57	KM Value [mM]
49	Localization
20	Metals/Ions
50	Molecular Weight [Da]
56	Natural Substrates/ Products (Substrates)
174	Organism
2	Oxidation Stability
9	Pathway
98	PDB ID
11	pH Optimum
4	pH Range
2	pH Stability
1	pI Value
26	Posttranslational Modification
9	Protein Variants
38	Purification (Commentary)
8	Reaction
1	Reaction Type
155	Reference
132	Source Tissue
20	Specific Activity [micromol/min/mg]
6	Storage Stability
153	Substrates and Products (Substrate)
37	Subunits
132	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]

Storage Stability

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Storage Stability on EC 2.3.3.8 - ATP citrate synthase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, 1 year, stable

Homo sapiens

-

488221

-20°C, 20% glycerol, stable up to 2 months

Rhodotorula toruloides

-

488217

-20°C, pH 8 stable for 4 months

Homo sapiens

-

488192

-20�C, stable

2 entries

4°C, 50 mM Tris-HCl, pH 7.5, 1 mM MgCl2, 10 mM 2-mercaptoethanol, 83% loss of activity after 48 h. 52% loss of activity in presence of 1 mM ATP. 30% loss of activity in presence of 20 mM citrate, 9% loss of activity in presence of 1 mM ATP and 20 mM citrate

Lipomyces starkeyi

-

488187

-20�C, stable

Rattus norvegicus

-

488213

-20�C, stable

Ricinus communis

-

488198