2.3.3.8: ATP citrate synthase

This is an abbreviated version!
For detailed information about ATP citrate synthase, go to the full flat file.

Word Map on EC 2.3.3.8

2.3.3.8

lipogenesis

carboxylase

lipogenic

malic

adipose

cholesterol

glucose-6-phosphate

triglyceride

histone

sterol

lipoprotein

hydroxycitrate

malate

adipocytes

6-phosphogluconate

acetyl-coenzyme

carnitine

isocitrate

oleaginous

statin

bempedoic

1.1.1.40

malonyl-coa

refeeding

cambogia

ezetimibe

stearoyl-coa

srebp-1

nadp-isocitrate

acetoacetyl-coa

6.4.1.2

garcinia

refeed

acetoacetate

analysis

drug development

synthesis

medicine

Reaction

Synonyms

ACL, ACL1, ACL2, ACLA, ACLB, ACLY, adenosine triphosphate citrate lyase, ATP citrate (pro-S)-lyase, ATP citrate lyase, ATP citrate lyase isoform 2, ATP-citrate lyase, ATP-citrate synthase A-2, ATP-citrate synthase alpha chain protein 2, ATP-citric lyase, ATP:citrate lyase, ATP:citrate oxaloacetate lyase ((pro-3S)-CH2COO--> acetyl-CoA) (ATP-dephosphorylating), ATP:citrate oxaloacetate-lyase (pro-3S-CH2COO->acetyl-CoA, ATP dephosphorylating), ATP:citrate oxaloacetate-lyase CoA-acetylating and ATP-dephosphorylating, Citrate cleavage enzyme, citrate-ATP lyase, citric cleavage enzyme, Earlier Degraded Tapetum1, EC 4.1.3.8, EDT1, Os11g0696200

ECTree

2 Transferases

2.3 Acyltransferases

2.3.3 Acyl groups converted into alkyl groups on transfer

2.3.3.8 ATP citrate synthase

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Results	in table
16	Activating Compound
7726	AA Sequence
12	Application
1	CAS Registry Number
23	Cloned(Commentary)
7	Crystallization (Commentary)
446	Disease/ Diagnostics
20	Expression
53	General Information
6	General Stability
18	IC50 Value
123	Inhibitors
3	kcat/KM [mM/s]
7	Ki Value [mM]
57	KM Value [mM]
49	Localization
20	Metals/Ions
50	Molecular Weight [Da]
56	Natural Substrates/ Products (Substrates)
174	Organism
2	Oxidation Stability
9	Pathway
98	PDB ID
11	pH Optimum
4	pH Range
2	pH Stability
1	pI Value
26	Posttranslational Modification
9	Protein Variants
38	Purification (Commentary)
8	Reaction
1	Reaction Type
155	Reference
132	Source Tissue
20	Specific Activity [micromol/min/mg]
6	Storage Stability
153	Substrates and Products (Substrate)
37	Subunits
132	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]

IC50 Value

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IC50 Value on EC 2.3.3.8 - ATP citrate synthase

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0.0212

1,3,8-trihydroxy-2-(3-methoxyphenyl)-6-methylanthracene-9,10-dione

Homo sapiens