1.14.14.17: squalene monooxygenase
This is an abbreviated version!
For detailed information about squalene monooxygenase, go to the full flat file.
Word Map on EC 1.14.14.17
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1.14.14.17
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cholesterol
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sterol
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terbinafine
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ergosterol
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trichophyton
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mevalonate
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lanosterol
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allylamine
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2,3-oxidosqualene
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hmg-coa
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itraconazole
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mentagrophytes
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rubrum
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oxidosqualene
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terbinafine-resistant
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tellurium
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tinea
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naftifine
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interdigitale
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antimycotic
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bloch
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griseofulvin
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dammarenediol
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dermatophytoses
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cycloartenol
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beta-amyrin
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medicine
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corporis
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drug development
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nutrition
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biotechnology
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pharmacology
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cholesterogenic
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synthesis
- 1.14.14.17
- cholesterol
- sterol
- terbinafine
- ergosterol
- trichophyton
- mevalonate
- lanosterol
- allylamine
- 2,3-oxidosqualene
- hmg-coa
- itraconazole
- mentagrophytes
- rubrum
- oxidosqualene
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terbinafine-resistant
- tellurium
- tinea
- naftifine
- interdigitale
-
antimycotic
-
bloch
-
griseofulvin
-
dammarenediol
-
dermatophytoses
- cycloartenol
- beta-amyrin
- medicine
-
corporis
- drug development
- nutrition
- biotechnology
- pharmacology
-
cholesterogenic
- synthesis
Reaction
Synonyms
CYP17, cytochrome P450 17alpha hydroxylase/17,20 lyase, EC 1.14.13.132, EC 1.14.99.7, Erg1, Erg1 protein, Erg1p, hydroxylase, squalene, oxygenase, squalene mono-, PgSQE1, PgSQE2, SE, SE1, SE3, SQE, SQE-I, SQE-II, sqe1, SQE3, SQLE, squalen expoxidase, squalene 2,3-epoxidase, squalene 2,3-oxidocyclase, squalene epoxidase, squalene epoxidase 1, squalene epoxidase 3, squalene hydroxylase, squalene mono-oxygenase, squalene oxydocyclase, squalene-2,3-epoxidase, squalene-2,3-epoxide cyclase, TkSQE1, TkSQE2, TkSQE3, TkSQE4
ECTree
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Source Tissue
Source Tissue on EC 1.14.14.17 - squalene monooxygenase
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latex-predominant isoform
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tumor cell defective in cytochrome P450 17alpha hydroxylase/17,20 lyase activity
additional information
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signal is significantly stronger in young leaves than in mature leaves
highest abundance of transcripts
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drought hypersensitive/squalene epoxidase 1-5 mutant has altered sterol composition in roots but wild-type sterol composition in shoots (GC-MS analysis)
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drought hypersensitive/squalene epoxidase 1-5 mutant has altered sterol composition in roots but wild-type sterol composition in shoots (GC-MS analysis)
high enzyme content, tissue distribution, in situ analysis, overview
highest abundance of transcripts
additional information
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PgSQE1 mRNA abundantly accumulates in all organs. PgSQE1 mRNA accumulates preferentially in vascular bundle tissue and resin ducts of petioles
additional information
PgSQE1 mRNA abundantly accumulates in all organs. PgSQE1 mRNA accumulates preferentially in vascular bundle tissue and resin ducts of petioles
additional information
Q75W20
PgSQE1 mRNA abundantly accumulates in all organs. PgSQE1 mRNA accumulates preferentially in vascular bundle tissue and resin ducts of petioles
additional information
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PgSQE2 is only weakly expressed and preferentially in petioles and flower buds. PgSQE2 mRNAs accumulates preferentially in vascular bundle tissue and resin ducts of petioles
additional information
PgSQE2 is only weakly expressed and preferentially in petioles and flower buds. PgSQE2 mRNAs accumulates preferentially in vascular bundle tissue and resin ducts of petioles
additional information
Q75W20
PgSQE2 is only weakly expressed and preferentially in petioles and flower buds. PgSQE2 mRNAs accumulates preferentially in vascular bundle tissue and resin ducts of petioles
additional information
transcripts are found in all tissues examined
additional information
transcripts are found in all tissues examined
additional information
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very low activity in non-cholesterogenic tissues: brain, muscle, lung, placenta, kidney