Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.14.17 extracted from

  • Tai, H.H.; Bloch, K.
    Squalene epoxidase of rat liver (1972), J. Biol. Chem., 247, 3767-3773.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information squalene epoxidation system requires a supernatant protein and a phospholipid: requirement for the heat-stable factor can be fully met by phosphatidylserine, phosphatidylglycerol or phosphatidylinositol and partially by other phospholipids, the heat-labile factor required is a protein with 44000 Da Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,1-bisnorsqualene + NADPH + O2
-
Rattus norvegicus 1,1-bisnor-squalene-2,3-epoxide + NADP+ + H2O
-
?
10,11-dihydrosqualene + NADPH + O2
-
Rattus norvegicus 10,11-dihydro-squalene-2,3-epoxide + NADP+ + H2O
-
?