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Information on EC 4.2.1.83 - 4-oxalomesaconate hydratase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.83 4-oxalomesaconate hydratase
IUBMB Comments
This enzyme participates in the degradation of 3,4-dihydroxybenzoate (via the meta-cleavage pathway), syringate and 3,4,5-trihydroxybenzoate, catalysing the reaction in the opposite direction [1-3]. It accepts the enol-form of 4-oxalomesaconate, 2-hydroxy-4-carboxy-hexa-2,4-dienedioate .
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The enzyme appears in viruses and cellular organisms
Synonyms
4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase, 4-carboxy-2-oxohexenedioate hydratase, 4-oxalmesaconate hydratase, 4-oxalomesaconate hydratase, gamma-oxalomesaconate hydratase, hydratase, oxalmesaconate, LigJ, OMA, OMA hydratase, oxalmesaconate hydratase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H2O
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