EC Number   |
General Information |
Reference |
|---|
    4.2.1.83 | evolution |
comparison of gene clusters of the protocatechuate 4,5-cleavage pathway in bacterial strains, overview |
-, 726779 |
| 4.2.1.83 | malfunction |
a pmdE knock out mutant loses the ability to grow on vanillate, 3-hydroxybenzoate, and 4-hydroxybenzoate as carbon sources. This ability to grow on vanillate, 3-hydroxybenzoate, and 4-hydroxybenzoate is restored by genetic complementation |
-, 726779 |
| 4.2.1.83 | metabolism |
the enzyme is active in the protocatechuate 4,5-cleavage pathway. Gene pmdU encodes an 4-oxalomesaconate tautomerase and catalyzes conversion of 4-oxalomesaconate-keto into 4-oxalomesaconate-enol, which is the only substrate of 4-oxalomesaconate hydratase. Pathway overview |
-, 726779 |
| 4.2.1.83 | physiological function |
the enzyme in strain CNB-1 is essential for growth on phenol, gentisate, vanillate, 3-hydroxybenzoate, and 4-hydroxybenzoate as carbon and energy sources |
-, 726779 |
