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Information on EC 4.2.1.135 - UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)

for references in articles please use BRENDA:EC4.2.1.135
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IUBMB Comments
Contains NAD+ as a cofactor . This is the first enzyme in the biosynthetic pathway of N,N'-diacetylbacillosamine , the first carbohydrate in the glycoprotein N-linked heptasaccharide in Campylobacter jejuni. This enzyme belongs to the short-chain dehydrogenase/reductase family of enzymes.
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The enzyme appears in viruses and cellular organisms
Synonyms
Bc3750, BC_3750, Cj1120c, Pdeg, PglF, UDP-Glc-NAc 4,6-dehydratase, UDP-N-acetylglucosamine C4,6-dehydratase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-N-acetyl-alpha-D-glucosamine = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O
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