EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.2.1.135 | more |
PglF catalyzes the formation of a UDP-4-oxo sugar with the appropriate stereochemistry at position 5'' from UDP-GlcNAc. Sugar capsule capsular polysaccharide A (CPSA), which coats the surface of the mammalian symbiont Bacteroides fragilis, is a key mediator of mammalian immune system development, the enzyme, coupled to a Bacteroides fragilis-encoded aminotransferase (WcfR), is used in sythetic construction system for CPSA for synthesis of the rare stereoconfiguration sugar acetamido-4-amino-6-deoxygalactopyranose in a two-step coupled reaction with WcfR, overview |
Campylobacter jejuni |
? |
- |
? |
4.2.1.135 | more |
product identification by mass spectrometry and one- and two-dimensional NMR analysis, substrate specificity analysis, overview. None of the UDP-sugars tested including UDP-galactose, UDPGalNAc, UDP-GlcNAc, and UDP-glucose are substrates for recombinant Pdeg |
Bacillus cereus |
? |
- |
? |
4.2.1.135 | more |
product identification by mass spectrometry and one- and two-dimensional NMR analysis, substrate specificity analysis, overview. None of the UDP-sugars tested including UDP-galactose, UDPGalNAc, UDP-GlcNAc, and UDP-glucose are substrates for recombinant Pdeg |
Bacillus cereus ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711 |
? |
- |
? |
4.2.1.135 | UDP-N-acetyl-alpha-D-glucosamine |
- |
Bacillus cereus |
UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O |
- |
? |
4.2.1.135 | UDP-N-acetyl-alpha-D-glucosamine |
PglF performs a cofactor-dependent hydride transfer from the C4 position of UDP-GlcNAc to C6, in conjunction with the elimination of water across the glucosyl C5 and C6 bond |
Campylobacter jejuni |
UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O |
- |
? |
4.2.1.135 | UDP-N-acetyl-alpha-D-glucosamine |
- |
Bacillus cereus ATCC 14579 |
UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O |
- |
? |
4.2.1.135 | UDP-N-acetyl-alpha-D-glucosamine |
- |
Bacillus cereus ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711 |
UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O |
- |
? |
4.2.1.135 | UDP-N-acetylglucosamine |
- |
Campylobacter jejuni |
? |
- |
? |
4.2.1.135 | UDP-N-acetylglucosamine |
- |
Campylobacter jejuni |
UDP-2-acetamido-2,6-dideoxy-alpha-D-4-ketohexulose + H2O |
- |
? |