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EC 3.3.2.14 Details
show Brenda entryEC number
3.3.2.14
Accepted name
2,4-dinitroanisole O-demethylase
Reaction
2,4-dinitroanisole + H2O = methanol + 2,4-dinitrophenol
Other name(s)
2,4-dinitroanisole ether hydrolase,
dnhA (gene name),
dnhB (gene name),
DNAN demethylase
Systematic name
2,4-dinitroanisole methanol hydrolase
Comment
The enzyme, characterized from the bacterium Nocardioides sp. JS1661, is involved in the degradation of 2,4-dinitroanisole. Unlike other known O-demethylases, such as EC 1.14.99.15, 4-methoxybenzoate monooxygenase (O-demethylating), or EC 1.14.11.32, codeine 3-O-demethylase, it does not require oxygen or electron donors, and produces methanol rather than formaldehyde.
History
created 2015
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1 Oxidoreductases
3 Hydrolases
3.3.2.1 isochorismatase
