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7.2.2.1: Na+-transporting two-sector ATPase

This is an abbreviated version!
For detailed information about Na+-transporting two-sector ATPase, go to the full flat file.

Word Map on EC 7.2.2.1

Reaction

ATP
+
H2O
 + n Na+[side 1] =
ADP
 +
phosphate
 + n Na+[side 2]

Synonyms

A1AO ATP synthase, ATP phosphohydrolase (Na+-transporting), ATP synthase, EC 3.6.3.15, F-type ATP synthase, F1FO-ATPase, KPA1, Lipid-binding protein, Na+ pump, Na+ V-ATPase, Na+(Li+, K+)/H+ antiporter, Na+-ATPase, Na+-translocating ATPase, Na+-translocating F1FO-ATPase, Na+-translocating V-ATPase, Na+-transporting FoF1 ATP synthase, Na+-transporting P-type ATPase, Na+-transporting two-sector ATPase, Na+-transporting V-ATPase, Ntp, sodium ion-pumping adenosine triphosphatase, UmpAB, V-ATPase, V-type Na+-ATPase, vacuolar Na+-translocating ATPase, vacuolar-type Na+-ATPase, vacuolar-type Na+-translocating ATPase, vacuole-type ATPase

ECTree

     7 Translocases
         7.2 Catalysing the translocation of inorganic cations
             7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
                7.2.2.1 Na+-transporting two-sector ATPase

Activating Compound

Activating Compound on EC 7.2.2.1 - Na+-transporting two-sector ATPase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3,5-di-tert-butyl-4-hydroxybenzylidenemalononitrile
-
i.e.SF 6847. Transport of Na+ is slightly stimulated, indicating that Na+ transport is electrogenic
ATP
-
ATP-induced stimulation of proximal tubule Na+-ATPase activity is mediated by a protein kinase C-dependent receptor P2Y2 and/or P2Y4 pathway
bafilomycin A1
-
stimulates ATP synthesis
Harmaline
-
stimulates ATP synthesis
NaHSO3
-
stimulates
sulfite
-
stimulates activity