6.3.4.6: urea carboxylase

This is an abbreviated version!
For detailed information about urea carboxylase, go to the full flat file.

Word Map on EC 6.3.4.6

Reaction

ATP
+
Urea
+
HCO3-
+
H+
=
ADP
+
phosphate
+
urea-1-carboxylate

Synonyms

Urease (ATP-hydrolysing), Urea carboxylase (hydrolysing), Urea amido-lyase, ATP:urea amidolyase, UALase, urea amidolyase, ATP-urea amidolyase, urea carboxylase, UCA, DUR1,2, KLLA0_E08119g

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.6 urea carboxylase

Reference

Reference on EC 6.3.4.6 - urea carboxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Roon, R.J.; Levenberg, B.
An adenosine triphosphate-dependent avidin-sensitive enzymatic cleavage of urea in yeast and green algae
J. Biol. Chem.
243
5213-5215
1968
Cyberlindnera jadinii, Pseudochlorella pringsheimii, Auxenochlorella pyrenoidosa
Manually annotated by BRENDA team
Whitney, P.A.; Cooper, T.G.
Urea carboxylase and allophanate hydrolase. Two components of adenosine triphosphate:urea amido-lyase in Saccharomyces cerevisiae
J. Biol. Chem.
247
1349-1353
1972
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Roon, R.J.; Levenberg, B.
Urea amidolyase. I. Properties of the enzyme from Candida utilis
J. Biol. Chem.
247
4107-4113
1972
Saccharomyces cerevisiae, Debaryomyces subglobosus, Cyberlindnera jadinii, Chlamydomonas reinhardtii, Pseudochlorella pringsheimii, Auxenochlorella pyrenoidosa
Manually annotated by BRENDA team
Whitney, P.A.; Cooper, T.G.
Urea carboxylase and allophanate hydrolase: two components of a multienzyme complex in Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
49
45-51
1972
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Roon, R.J.; Hampshire, J.; Levenberg, B.
Urea amidolyase. The involvement of biotin in urea cleavage
J. Biol. Chem.
247
7539-7545
1972
Saccharomyces cerevisiae, Cyberlindnera jadinii
Manually annotated by BRENDA team
Whitney, P.A.; Cooper, T.
Urea carboxylase from Saccharomyces cerevisiae. Evidence for a minimal two-step reaction sequence
J. Biol. Chem.
248
325-330
1973
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Leftley, J.W.; Syrett, P.J.
Urease and ATP: urea amidolyase activity in unicellular algae
J. Gen. Microbiol.
77
109-115
1973
Ankistrodesmus braunii, Asterococcus superbus, Chlamydomonas reinhardtii, Chlorophyceae, Dunaliella primolecta, Nannochloris bacillaris, Marvania coccoides, Scenedesmus basiliensis, Tetradesmus obliquus
-
Manually annotated by BRENDA team
Castric, P.A.; Levenberg, B.
Urea amidolyase of Candida utilis. Characterization of the urea cleavage reactions
Biochim. Biophys. Acta
438
574-583
1976
Cyberlindnera jadinii
Manually annotated by BRENDA team
Waheed, A.; Castric, P.A.
Purification and properties of the urea amidolyase from Candida utilis
J. Biol. Chem.
252
1628-1632
1977
Cyberlindnera jadinii
Manually annotated by BRENDA team
Metz, W.; Reuter, G.
Anabole und katabole Enzyme des Harnstoffmetabolismus in einem kohlenwasserstoffverwertenden Stamm von Candida guilliermondii
Z. Allg. Mikrobiol.
17
599-610
1977
Meyerozyma guilliermondii
Manually annotated by BRENDA team
Sumrada, R.A.; Cooper, T.G.
Urea carboxylase and allophanate hydrolase are components of a multifunctional protein in yeast
J. Biol. Chem.
257
9119-9127
1982
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Rees, T.A.V.; Bekheet, I.A.
The role of nickel in urea assimilation by algae
Planta
156
386-387
1982
[Chlorella] fusca
-
Manually annotated by BRENDA team
Kimura, S.; Iyama, S.; Yamaguchi, Y.; Hayashi, S.; Fushimi, R.; Amino, N.
New enzymatic assay with urea amidolyase for determining potassium in serum
Ann. Clin. Biochem.
34
384-388
1997
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Genbauffe, F.S.; Cooper, T.G.
The urea amidolyase (DUR1,2) gene of Saccharomyces cerevisiae
DNA Seq.
2
19-32
1991
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Jones, R.A.; Montague, M.J.; Taylor, J.
Urease and urea amidolyase determination of activity in liverworts
Phytochemistry
12
1675-1676
1973
no activity in Marchantia polymorpha
-
Manually annotated by BRENDA team
Kimura, S.; Iyama, S.; Yamaguchi, Y.; Kanakura, Y.
New enzymatic assay for serum urea nitrogen using urea amidolyase
J. Clin. Lab. Anal.
17
52-56
2003
Saccharomyces cerevisiae (P32528), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kanamori, T.; Kanou, N.; Atomi, H.; Imanaka, T.
Enzymatic characterization of a prokaryotic urea carboxylase
J. Bacteriol.
186
2532-2539
2004
Oleomonas sagaranensis (Q75RY4), Oleomonas sagaranensis
Manually annotated by BRENDA team
Navarathna, D.H.; Harris, S.D.; Roberts, D.D.; Nickerson, K.W.
Evolutionary aspects of urea utilization by fungi
FEMS Yeast Res.
10
209-213
2010
Eremothecium gossypii, Aspergillus fumigatus, Aspergillus nidulans, Candida albicans, [Candida] glabrata, Fusarium graminearum, Kluyveromyces lactis, Pyricularia grisea, Clavispora lusitaniae, Parastagonospora nodorum, Saccharomyces cerevisiae (P32528)
Manually annotated by BRENDA team
Navarathna, D.; Das, A.; Morschhauser, J.; Nickerson, K.; Roberts, D.
Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2
Microbiology
157
270-279
2011
Candida albicans
Manually annotated by BRENDA team
Strope, P.K.; Nickerson, K.W.; Harris, S.D.; Moriyama, E.N.
Molecular evolution of urea amidolyase and urea carboxylase in fungi
BMC Evol. Biol.
11
80
2011
Aspergillus fumigatus, Aspergillus nidulans, Aspergillus terreus, Bipolaris maydis, Cryptococcus neoformans, Fusarium oxysporum, Fusarium verticillioides, Fusarium solani, Nitrosomonas europaea, Parastagonospora nodorum, Sorangium cellulosum
Manually annotated by BRENDA team
Fan, C.; Chou, C.Y.; Tong, L.; Xiang, S.
Crystal structure of urea carboxylase provides insights into the carboxyltransfer reaction
J. Biol. Chem.
287
9389-9398
2012
Kluyveromyces lactis (Q6CP22), Kluyveromyces lactis ATCC 8585 (Q6CP22), Kluyveromyces lactis
Manually annotated by BRENDA team
Zhao, J.; Zhu, L.; Fan, C.; Wu, Y.; Xiang, S.
Structure and function of urea amidolyase
Biosci. Rep.
38
pii: BSR20171617
2018
Kluyveromyces lactis (Q6CP22), Kluyveromyces lactis DSM 70799 (Q6CP22)
Manually annotated by BRENDA team
Lin, Y.; Boese, C.; St. Maurice, M.
The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent
Protein Sci.
25
1812-1824
2016
Pseudomonas syringae pv. tomato, Pseudomonas syringae pv. tomato ATCC BAA-871
Manually annotated by BRENDA team