6.3.4.6: urea carboxylase

This is an abbreviated version!
For detailed information about urea carboxylase, go to the full flat file.

Word Map on EC 6.3.4.6

Reaction

ATP
+
Urea
+
HCO3-
+
H+
=
ADP
+
phosphate
+
urea-1-carboxylate

Synonyms

Urease (ATP-hydrolysing), Urea carboxylase (hydrolysing), Urea amido-lyase, ATP:urea amidolyase, UALase, urea amidolyase, ATP-urea amidolyase, urea carboxylase, UCA, DUR1,2, KLLA0_E08119g

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.6 urea carboxylase

Systematic Name

Systematic Name on EC 6.3.4.6 - urea carboxylase

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SYSTEMATIC NAME
IUBMB Comments
urea:carbon-dioxide ligase (ADP-forming)
A biotinyl-protein. The yeast enzyme (but not that from green algae) also catalyses the reaction of EC 3.5.1.54 allophanate hydrolase, thus bringing about the hydrolysis of urea to CO2 and NH3. Previously also listed as EC 3.5.1.45. The enzyme from the prokaryotic bacterium Oleomonas sagaranensis can also use acetamide and formamide as substrates [4].