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6.3.4.6: urea carboxylase

This is an abbreviated version!
For detailed information about urea carboxylase, go to the full flat file.

Word Map on EC 6.3.4.6

Reaction

ATP
+
Urea
+
HCO3-
+
H+
=
ADP
+
phosphate
+
urea-1-carboxylate

Synonyms

ATP-urea amidolyase, ATP:urea amidolyase, DUR1,2, EC 3.5.1.45, KLLA0_E08119g, UALase, UCA, Urea amido-lyase, urea amidolyase, urea carboxylase, Urea carboxylase (hydrolysing), Urease (ATP-hydrolysing)

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.6 urea carboxylase

pH Range

pH Range on EC 6.3.4.6 - urea carboxylase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.5 - 8.5
pH 6.5: about 80% of maximal activity, pH 8.5: about 45% of maximal activity, Hepes-NaOH buffer
7.2 - 9
-
pH 7.2: about 50% of maximal activity, pH 9.0: about 30% of maximal activity
7.3 - 8.7
-
about 50% of maximal activity at pH 7.3 and 8.7