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4.2.3.1: threonine synthase

This is an abbreviated version!
For detailed information about threonine synthase, go to the full flat file.

Word Map on EC 4.2.3.1

Reaction

O-phospho-L-homoserine
+
H2O
=
L-threonine
 +
phosphate

Synonyms

EC 4.2.99.2, MtTS, synthase, threonine, THR4, threonine synthase, threonine synthase (gene MA1610), threonine synthetase, ThrS, TS

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.1 threonine synthase

Inhibitors

Inhibitors on EC 4.2.3.1 - threonine synthase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
AMP-derivatives
-
-
-
DL-2-amino-3[(phosphonomethyl)thio]propionic acid
-
Ki: 0.057 mM, kinact: 1.44 min-1
DL-E-2-amino-5-phosphono-4-pentenoic acid
-
Ki: 0.54 mM
GMP
-
25% inhibition at 67 mM
IMP
-
23% inhibition at 67 mM
KCN
-
22% inhibition at 1 mM
L-2,3-methanohomoserine phosphate
-
Ki: 0.01 mM
L-2-amino-3[(phosphonomethyl)thio]propionic acid
L-3-hydroxyhomoserine
-
Ki: 0.05 mM
L-cysteine
L-threo-3-hydroxyhomoserine
NH2OH
-
65% inhibition at 1 mM
O-phospho-DL-threonine
-
-
O-phospho-L-serine
-
-
phosphate
phospho-threonine
-
35% inhibition at 10 mM
phosphonovaleric acid
-
Ki: 0.031 mM
Vinylglycine
-
22% inhibition at 10 mM