4.2.1.18: methylglutaconyl-CoA hydratase

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For detailed information about methylglutaconyl-CoA hydratase, go to the full flat file.

Word Map on EC 4.2.1.18

4.2.1.18

acidurias

3-methylglutaconic

urine

inborn

3-methylglutaric

speech

3-methylcrotonyl-coa

3-hydroxyisovaleric

hypotonia

enoyl-coas

psychomotor

isovaleryl-coa

thiolase

medicine

Reaction

Synonyms

(3S)-methylglutaconyl-CoA hydratase, 3-methylglutaconyl CoA hydratase, 3-methylglutaconyl-CoA hydratase, 3-MG-CoA, 3-MGCoA-H, 3MGH, At4g16800, AU RNA binding protein/enoyl-Coenzyme A hydratase, AUH, HMG-CoA hydrolyase, hydratase, methylglutaconyl coenzyme A, LiuC, methylglutaconase, methylglutaconyl coenzyme A hydratase, MG-CoA hydratase, MGCH, Tb427.10.4000

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.18 methylglutaconyl-CoA hydratase

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Results	in table
699	AA Sequence
3	Application
1	CAS Registry Number
7	Cloned(Commentary)
1	Cofactor
2	Crystallization (Commentary)
59	Disease/ Diagnostics
4	General Information
4	Inhibitors
1	kcat/KM [mM/s]
2	Ki Value [mM]
18	KM Value [mM]
5	Localization
1	Metals/Ions
6	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
27	Organism
6	Pathway
12	PDB ID
2	pH Optimum
2	pH Range
15	Protein Variants
4	Purification (Commentary)
2	Reaction
1	Reaction Type
22	Reference
11	Source Tissue
4	Specific Activity [micromol/min/mg]
38	Substrates and Products (Substrate)
4	Subunits
32	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
16	Turnover Number [1/s]

Cloned

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Cloned on EC 4.2.1.18 - methylglutaconyl-CoA hydratase

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Pseudomonas putida

664032

expressed in Escherichia coli, amino acid sequence determined, membership to the crotonase/isomerase super family classified by comparing protein seqences, up to 50% identity to amino acid sequences of more than 100 prokaryotic enoyl-CoA hydratases, 30% homology to the gene product of human AUH gene

Acinetobacter sp.

Q3HW12

677848

expression in Escherichia coli

3 entries

gene AUH, genotyping

Homo sapiens

716241

overexpression in Escherichia coli using the pMAL-c2 expression vector

Homo sapiens

Q13825

679737