4.2.1.18: methylglutaconyl-CoA hydratase

This is an abbreviated version!
For detailed information about methylglutaconyl-CoA hydratase, go to the full flat file.

Word Map on EC 4.2.1.18

Reaction

(S)-3-hydroxy-3-methylglutaryl-CoA
=
trans-3-methylglutaconyl-CoA
+
H2O

Synonyms

hydratase, methylglutaconyl coenzyme A, methylglutaconyl coenzyme A hydratase, 3-methylglutaconyl CoA hydratase, methylglutaconase, MG-CoA hydratase, HMG-CoA hydrolyase, AUH, (3S)-methylglutaconyl-CoA hydratase, MGCH, 3MGH, 3-methylglutaconyl-CoA hydratase, 3-MG-CoA, AU RNA binding protein/enoyl-Coenzyme A hydratase, LiuC, Tb427.10.4000, 3-MGCoA-H, At4g16800

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.18 methylglutaconyl-CoA hydratase

Substrates Products

Substrates Products on EC 4.2.1.18 - methylglutaconyl-CoA hydratase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(E)-3-methylglutaconyl-1-CoA
?
show the reaction diagram
different co-substrates tested
-
-
?
(E)-glutaconyl-CoA
?
show the reaction diagram
(R,S)-3-hydroxy-3-methylglutaryl-CoA
?
show the reaction diagram
different co-substrates tested
-
-
?
(S)-3-Hydroxy-3-methylglutaryl-CoA
?
show the reaction diagram
(S)-3-hydroxy-3-methylglutaryl-CoA
trans-3-methylglutaconyl-CoA + H2O
show the reaction diagram
(S)-3-hydroxyglutaryl-CoA
?
show the reaction diagram
3-hydroxybutyryl-CoA
?
show the reaction diagram
different co-substrates tested
-
-
?
3-methylcrotonyl-CoA
?
show the reaction diagram
different co-substrates tested
-
-
?
3-methylglutaconyl-CoA
?
show the reaction diagram
crotonyl-CoA
?
show the reaction diagram
different co-substrates tested
-
-
?
trans-3-methylglutaconyl-CoA + H2O
(S)-3-hydroxy-3-methylglutaryl-CoA
show the reaction diagram
-
-
-
?
trans-3-methylglutaconyl-CoA + H2O
(S)-3-hydroxymethylglutaryl-CoA
show the reaction diagram
additional information
?
-