3.5.3.12: agmatine deiminase

This is an abbreviated version!
For detailed information about agmatine deiminase, go to the full flat file.

Reaction

Synonyms

AgD, AgDI, agmatine amidinohydrolase, agmatine deiminase, agmatine deiminaseHpAgD, agmatine iminohydrolase, agu2A, AguA, aguA protein, AguA1, aguA2, AIH, More, PgAgD, putrescine synthase, SmAgD

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.3 In linear amidines

                3.5.3.12 agmatine deiminase

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Results	in table
20	Activating Compound
6166	AA Sequence
16	Application
1	CAS Registry Number
11	Cloned(Commentary)
3	Crystallization (Commentary)
11	Expression
15	General Information
2	General Stability
17	IC50 Value
131	Inhibitors
20	kcat/KM [mM/s]
5	Ki Value [mM]
17	KM Value [mM]
6	Localization
33	Molecular Weight [Da]
53	Natural Substrates/ Products (Substrates)
164	Organism
6	Pathway
31	PDB ID
42	pH Optimum
9	pH Range
2	pH Stability
2	Posttranslational Modification
25	Protein Variants
24	Purification (Commentary)
6	Reaction
6	Reaction Type
103	Reference
33	Source Tissue
35	Specific Activity [micromol/min/mg]
8	Storage Stability
123	Substrates and Products (Substrate)
22	Subunits
85	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
2	Temperature Range [°C]
7	Temperature Stability [°C]
6	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 3.5.3.12 - agmatine deiminase

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0000038 - 0.0000235

Ac-SGRGK

2 entries

0.0283 - 53

agmatine

6 entries

0.0000678 - 0.0000812

guanidine

2 entries

0.000017 - 0.000149

L-arginine

2 entries

0.000072 - 0.0001285

N-alpha-benzoyl-L-arginine amide

2 entries

0.0000847 - 0.0001383

N-alpha-benzoyl-L-arginine ethyl ester

2 entries

0.0001038 - 0.0002183

N-alpha-benzoyl-L-arginine methyl ester

2 entries

0.000033 - 0.0000377

streptomycin

2 entries

0.0000038

Ac-SGRGK

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375

0.0000235

Ac-SGRGK

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.0283

agmatine

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.136

agmatine

Pseudomonas aeruginosa PA14

A0A0H2Z743, A0A0H2Z8C6

pH 9.0, 25°C

713057

1.57

agmatine

Listeria monocytogenes serotype 1/2a

A0A0H3G8U9

pH 7.5, 25°C

752712

2.45

agmatine

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375

2.624

agmatine

Pseudomonas aeruginosa PA14

A0A0H2Z743, A0A0H2Z8C6

pH 9.0, 37°C

713057

53

agmatine

Listeria monocytogenes

-

at 25°C and pH 7.5

734228

0.0000678

guanidine

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.0000812

guanidine

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375

0.000017

L-arginine

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375

0.000149

L-arginine

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.000072

N-alpha-benzoyl-L-arginine amide

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375

0.0001285

N-alpha-benzoyl-L-arginine amide

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.0000847

N-alpha-benzoyl-L-arginine ethyl ester

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375

0.0001383

N-alpha-benzoyl-L-arginine ethyl ester

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.0001038

N-alpha-benzoyl-L-arginine methyl ester

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375

0.0002183

N-alpha-benzoyl-L-arginine methyl ester

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.000033

streptomycin

Helicobacter pylori

Q9ZN18

mutant D198A, pH 8.0, 37°C

711375

0.0000377

streptomycin

Helicobacter pylori

Q9ZN18

wild-type, pH 8.0, 37°C

711375