3.5.3.12: agmatine deiminase

This is an abbreviated version!
For detailed information about agmatine deiminase, go to the full flat file.

Reaction

Synonyms

AgD, AgDI, agmatine amidinohydrolase, agmatine deiminase, agmatine deiminaseHpAgD, agmatine iminohydrolase, agu2A, AguA, aguA protein, AguA1, aguA2, AIH, More, PgAgD, putrescine synthase, SmAgD

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.3 In linear amidines

                3.5.3.12 agmatine deiminase

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Results	in table
20	Activating Compound
6166	AA Sequence
16	Application
1	CAS Registry Number
11	Cloned(Commentary)
3	Crystallization (Commentary)
11	Expression
15	General Information
2	General Stability
17	IC50 Value
131	Inhibitors
20	kcat/KM [mM/s]
5	Ki Value [mM]
17	KM Value [mM]
6	Localization
33	Molecular Weight [Da]
53	Natural Substrates/ Products (Substrates)
164	Organism
6	Pathway
31	PDB ID
42	pH Optimum
9	pH Range
2	pH Stability
2	Posttranslational Modification
25	Protein Variants
24	Purification (Commentary)
6	Reaction
6	Reaction Type
103	Reference
33	Source Tissue
35	Specific Activity [micromol/min/mg]
8	Storage Stability
123	Substrates and Products (Substrate)
22	Subunits
85	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
2	Temperature Range [°C]
7	Temperature Stability [°C]
6	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 3.5.3.12 - agmatine deiminase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

agmatine

5 entries

AguR regulator

Enterococcus faecalis

-

-

735102

-

histamine

2 entries

L-lactic acid

Lentilactobacillus hilgardii

-

shows a stimulatory effect on activity

687349

spermidine

Pseudomonas aeruginosa

Q9I6J9

at concentration of 0.1 g/l about 10% more putrescine production, at concentration of 1 g/l 32% more putrescine production

692430

spermine

Pseudomonas aeruginosa

Q9I6J9

at concentration of 0.1 g/l about 2% more putrescine production, at concentration of 1 g/l 23% more putrescine production

692430

succinate

2 entries

tartaric acid

Lentilactobacillus hilgardii

-

shows a stimulatory effect on activity

687349

tyramine

2 entries

Urea

Evernia prunastri

-

-

209401

additional information

4 entries

-

agmatine

Streptococcus criceti

-

-

700535

agmatine

Streptococcus downei

-

-

700535

agmatine

Streptococcus mutans

-

-

700535

agmatine

Streptococcus ratti

-

-

700535

agmatine

Streptococcus sobrinus

-

-

700535

histamine

Lentilactobacillus hilgardii

-

at concentration of 0.1 g/l about 2% more putrescine production, at concentration of 1 g/l about 5% more putrescine production

692430

histamine

Pseudomonas aeruginosa

Q9I6J9

at concentration of 0.1 g/l and 1.0 g/l about 10% more putrescine production

692430

succinate

Bacillus cereus

-

at concentration of 1 g/l about 5% more putrescine production

692430

succinate

Pseudomonas aeruginosa

Q9I6J9

at concentration of 0.1 g/l about 15% more putrescine production, at concentration of 1 g/l about 35% more putrescine production

692430

tyramine

Lentilactobacillus hilgardii

-

at concentration of 1 g/l about 2% more putrescine production

692430

tyramine

Pseudomonas aeruginosa

Q9I6J9

at concentration of 0.1 g/l about 15% more putrescine production, at concentration of 1 g/l 20% more putrescine production

692430

additional information

Lentilactobacillus hilgardii

-

ornithine, D-lactic acid, citric acid, L-malic acid, and DL-malic acid do not modify activity

687349

-

additional information

Pseudomonas aeruginosa

-

diverse polyamines and sugars increased putrescine production, e.g. succinic acid increases putrescine production, but does not alter agmatine deimination, overview

692430

-

additional information

Pseudomonas aeruginosa

Q9I6J9

diverse polyamines and sugars increased putrescine production, e.g. succinic acid increases putrescine production, but does not alter agmatine deimination, overview

692430

-

additional information

Streptococcus mutans

-

2fold higher expression of aguB in presence of 10 mM agmatine, 2fold higher activity at pH 5.5

695768

-