3.5.3.12: agmatine deiminase

This is an abbreviated version!
For detailed information about agmatine deiminase, go to the full flat file.

Reaction

Synonyms

AgD, AgDI, agmatine amidinohydrolase, agmatine deiminase, agmatine deiminaseHpAgD, agmatine iminohydrolase, agu2A, AguA, aguA protein, AguA1, aguA2, AIH, More, PgAgD, putrescine synthase, SmAgD

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.3 In linear amidines

                3.5.3.12 agmatine deiminase

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Results	in table
20	Activating Compound
6166	AA Sequence
16	Application
1	CAS Registry Number
11	Cloned(Commentary)
3	Crystallization (Commentary)
11	Expression
15	General Information
2	General Stability
17	IC50 Value
131	Inhibitors
20	kcat/KM [mM/s]
5	Ki Value [mM]
17	KM Value [mM]
6	Localization
33	Molecular Weight [Da]
53	Natural Substrates/ Products (Substrates)
164	Organism
6	Pathway
31	PDB ID
42	pH Optimum
9	pH Range
2	pH Stability
2	Posttranslational Modification
25	Protein Variants
24	Purification (Commentary)
6	Reaction
6	Reaction Type
103	Reference
33	Source Tissue
35	Specific Activity [micromol/min/mg]
8	Storage Stability
123	Substrates and Products (Substrate)
22	Subunits
85	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
2	Temperature Range [°C]
7	Temperature Stability [°C]
6	Turnover Number [1/s]

pH Range

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pH Range on EC 3.5.3.12 - agmatine deiminase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

3.5 - 10.5

Listeria monocytogenes

-

more than 85% activity between pH 3.5 and 10.5

734228

4.5 - 10.5

Zea mays

-

-

209396

5 - 7

Streptococcus mutans

-

AgD induction clearly enhanced at low pH values, aguA ca. 3.7fold higher in cells grown at pH 5 than that grown at pH 7, stress response pathway of this organism

669131

5 - 9

Glycine max

-

-

209395

5.5 - 9.5

Listeria monocytogenes serotype 1/2a

A0A0H3G8U9

pH 5.5: about 60% of maximal activity, pH 9.5: about 65% of maximal activity

752712

6

Zea mays

-

purified enzyme shows 85% of maximum activity

670510

6 - 7

Zea mays

-

activity rapidly declining below pH 6.0 and declining less rapidly above pH 7.0

209398

6.5 - 8

Cucumis sativus

-

89% of maximal activity at pH 6.5, 91% of maximal activity at pH 8.0

657259

8

Zea mays

-

purified enzyme shows 85% of maximum activity

670510