1.5.1.24: N5-(carboxyethyl)ornithine synthase

This is an abbreviated version!
For detailed information about N5-(carboxyethyl)ornithine synthase, go to the full flat file.

Word Map on EC 1.5.1.24

Reaction

N5-(L-1-carboxyethyl)-L-ornithine
+
NADP+
+
H2O
=
L-ornithine
+
pyruvate
+
NADPH
+
H+

Synonyms

bCEOS, CBO0515, CEOS, N(5)-(L-1-carboxyethyl)-L-ornithine:NADP(+) oxidoreductase, N5-(carboxyethyl) ornithine synthase, N5-(CE) ornithine synthase, N5-CEO synthase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.24 N5-(carboxyethyl)ornithine synthase

Substrates Products

Substrates Products on EC 1.5.1.24 - N5-(carboxyethyl)ornithine synthase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
alpha-N-acetylornithine + pyruvate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
D-lysine + pyruvate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
enzyme also reacts with D-isomer
-
-
?
D-ornithine + pyruvate + NADPH + H+
N5-(L-1-carboxyethyl)-D-ornithine + NADP+ + H2O
show the reaction diagram
enzyme also reacts with D-isomer
-
-
?
L-lysine + pyruvate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
L-ornithine + 2-oxo-butanoic acid + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
L-ornithine + 3-fluoropyruvic acid + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
L-ornithine + 3-mercaptopyruvic acid + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
L-ornithine + glyoxylic acid + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
L-ornithine + methylglyoxal + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
L-ornithine + oxaloacetic acid + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
L-ornithine + pyruvate + NADPH
N5-(L-1-carboxyethyl)-L-ornithine + NADP+ + H2O
show the reaction diagram
L-ornithine + pyruvate + NADPH + H+
N5-(L-1-carboxyethyl)-L-ornithine + NADP+ + H2O
show the reaction diagram
highest reaction rate
-
-
?
lysine + pyruvate + NADPH
N7-(1-carboxyethyl)lysine + NADP+ + H2O
show the reaction diagram
N2-methylornithine + pyruvate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
N6-hydroxy-L-lysine + pyruvate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
O-(2-aminoethyl)-L-serine + pyruvate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?
ornithine + 3-fluoropyruvate + NADPH
N6-(1-carboxy-2-fluoroethyl)ornithine + NADP+ + H2O
show the reaction diagram
-
slight activity observed, about 15% of the rate found with pyruvate
-
-
?
S-(2-aminoethyl)-L- cysteine + pyruvate + NADPH + H+
? + NADP+ + H2O
show the reaction diagram
weak reaction rate
-
-
?