1.3.8.4: isovaleryl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about isovaleryl-CoA dehydrogenase, go to the full flat file.

Reaction

Synonyms

acyl-CoA dehydrogenase, EC 1.3.99.10, i3VD, iso(3)valeryl-CoA dehydrogenase, isovaleric-CoA dehydrogenase, isovaleroyl-coenzyme A dehydrogenase, isovaleryl-coenzyme A dehydrogenase, IVD, IVDH, LiuA, Pden_3633, SBCAD, short/branched chain acyl-CoA dehydrogenase

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.8 With a flavin as acceptor

                1.3.8.4 isovaleryl-CoA dehydrogenase

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Results	in table
4	Activating Compound
4063	AA Sequence
3	Application
1	CAS Registry Number
21	Cloned(Commentary)
21	Cofactor
1	Crystallization (Commentary)
88	Disease/ Diagnostics
2	Expression
27	General Information
33	Inhibitors
6	kcat/KM [mM/s]
6	Ki Value [mM]
59	KM Value [mM]
25	Localization
18	Molecular Weight [Da]
57	Natural Substrates/ Products (Substrates)
53	Organism
5	Pathway
10	pH Optimum
49	Protein Variants
15	Purification (Commentary)
1	Reaction
3	Reaction Type
52	Reference
1	Renatured (Commentary)
31	Source Tissue
75	Specific Activity [micromol/min/mg]
1	Storage Stability
136	Substrates and Products (Substrate)
8	Subunits
34	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
7	Temperature Stability [°C]
17	Turnover Number [1/s]

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RENATURED/Commentary

ORGANISM

UNIPROT

LITERATURE

the recombinant IVDH enzyme mutant E246Q is obtained as an apoprotein, the protein is fully reconstituted to the holoprotein by incubation with flavin adenine dinucleotide (FAD) at a ratio 1:20 (IVDH: FAD) molar excess. The reconstituted E246Q IVDH has no activity for isovaleryl-CoA

Paracoccus denitrificans

A1B856

763557