1.2.1.99: 4-(gamma-glutamylamino)butanal dehydrogenase

This is an abbreviated version!
For detailed information about 4-(gamma-glutamylamino)butanal dehydrogenase, go to the full flat file.

Reaction

4-(gamma-L-glutamylamino)butanal
+
NAD(P)+
+
H2O
=
4-(gamma-L-glutamylamino)butanoate
+
NAD(P)H
+
H+

Synonyms

ALDH, gamma-Glu-gamma-aminobutyraldehyde dehydrogenase, gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [NAD(P)+], NAD+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase, PuuC

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase

Specific Activity

Specific Activity on EC 1.2.1.99 - 4-(gamma-glutamylamino)butanal dehydrogenase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.3
Vmax: 3-hydroxypropionate, pH 8.0, 37°C, cofactor: NADH
1.5
-
recombinant KpBC_DELTA_dhaT_DELTA_yqhD strain, pH 8.0, 45°C
12.39
Vmax: acetaldehyde, pH 8.0, 37°C, cofactor: NAD+
19.51
Vmax: benzaldehyde, pH 8.0, 37°C, cofactor: NAD+
2.5
-
recombinant KpC_DELTA_dhaT_DELTA_yqhD strain, pH 8.0, 45°C
22.25
-
Vmax: 3-hydroxypropionaldehyde, pH 8.0, 45°C
27.35
Vmax: propionaldehyde, pH 8.0, 37°C, cofactor: NAD+
28.61
-
Vmax: isovaleraldehyde, pH 8.0, 45°C
29.47
Vmax: valeraldehyde, pH 8.0, 37°C, cofactor: NAD+
30.07
Vmax: butyraldehyde, pH 8.0, 37°C, cofactor: NAD+
30.67
Vmax: isovaleraldehyde, pH 8.0, 37°C, cofactor: NAD+
32.1
Vmax: 3-hydroxypropionaldehyde, pH 8.0, 37°C, cofactor: NAD+
33.26
-
Vmax: valeraldehyde, pH 8.0, 45°C
34.08
-
Vmax: butyraldehyde, pH 8.0, 45°C
5.5
Vmax: 3-hydroxypropionaldehyde, pH 8.0, 37°C, cofactor: NADP+
additional information
-
activity varies depending on the type of strain and culture conditions, e.g. aeration conditions and working volume