1.2.1.99: 4-(gamma-glutamylamino)butanal dehydrogenase

This is an abbreviated version!
For detailed information about 4-(gamma-glutamylamino)butanal dehydrogenase, go to the full flat file.

Reaction

4-(gamma-L-glutamylamino)butanal
+
NAD(P)+
+
H2O
=
4-(gamma-L-glutamylamino)butanoate
+
NAD(P)H
+
H+

Synonyms

ALDH, gamma-Glu-gamma-aminobutyraldehyde dehydrogenase, gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [NAD(P)+], NAD+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase, PuuC

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase

General Information

General Information on EC 1.2.1.99 - 4-(gamma-glutamylamino)butanal dehydrogenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
PuuC is a nonspecific aldehyde dehydrogenase that oxidizes all the aldehydes in putrescine catabolism. Strains lacking PuuC activity have a doubling time 50% greater than the wild type with putrescine as the sole nitrogen source. Strains with deletions of putrescine aminotransferase PatA and any of PuuA, PuuB, or PuuC do not grow with putrescine as the nitrogen source