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1.14.14.57: taurochenodeoxycholate 6alpha-hydroxylase

This is an abbreviated version!
For detailed information about taurochenodeoxycholate 6alpha-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.57

Reaction

lithocholate
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
hyodeoxycholate
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP3A4, CYP4A21, EC 1.14.13.97, taurochenodeoxycholate 6alpha-monooxygenase, taurochenodeoxycholic acid 6alpha-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.57 taurochenodeoxycholate 6alpha-hydroxylase

General Information

General Information on EC 1.14.14.57 - taurochenodeoxycholate 6alpha-hydroxylase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
-
a strong correlation exists between 6alpha-hydroxylation of taurochenodeoxycholic acid, CYP3A levels and testosterone 6beta-hydroxylation. There is also a strong correlation between 6alpha-hydroxylation of lithocholic acid, CYP3A levels and testosterone 6beta-hydroxylation