1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about L-2-hydroxycarboxylate dehydrogenase [NAD(P)+], go to the full flat file.

Word Map on EC 1.1.1.375

Reaction

a (2S)-2-hydroxycarboxylate
+
NAD(P)+
=
a 2-oxocarboxylate
+
NAD(P)H
+
H+

Synonyms

MdhII, lactate/malate dehydrogenase, MJ0490, MJ0409, LDH-like L-MalDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

Reference

Reference on EC 1.1.1.375 - L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Graupner, M.; Xu, H.; White, R.H.
Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaea
J. Bacteriol.
182
3688-3692
2000
Methanocaldococcus jannaschii (Q60176), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q60176)
Manually annotated by BRENDA team
Madern, D.; Ebel, C.; Dale, H.A.; Lien, T.; Steen, I.H.; Birkeland, N.K.; Zaccai, G.
Differences in the oligomeric states of the LDH-like L-MalDH from the hyperthermophilic archaea Methanococcus jannaschii and Archaeoglobus fulgidus
Biochemistry
40
10310-10306
2001
Archaeoglobus fulgidus (O08349), Archaeoglobus fulgidus, Methanocaldococcus jannaschii (Q60176), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q60176)
Manually annotated by BRENDA team
Lee, B.I.; Chang, C.; Cho, S.J.; Eom, S.H.; Kim, K.K.; Yu, Y.G.; Suh, S.W.
Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases
J. Mol. Biol.
307
1351-1362
2001
Methanocaldococcus jannaschii (Q60176), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q60176)
Manually annotated by BRENDA team
Madern, D.
The putative L-lactate dehydrogenase from Methanococcus jannaschii is an NADPH-dependent L-malate dehydrogenase
Mol. Microbiol.
37
1515-1520
2000
Methanocaldococcus jannaschii (Q60176), Methanocaldococcus jannaschii DSM 2661 (Q60176)
Manually annotated by BRENDA team