1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about L-2-hydroxycarboxylate dehydrogenase [NAD(P)+], go to the full flat file.

Word Map on EC 1.1.1.375

Reaction

a (2S)-2-hydroxycarboxylate
+
NAD(P)+
=
a 2-oxocarboxylate
+
NAD(P)H
+
H+

Synonyms

MdhII, lactate/malate dehydrogenase, MJ0490, MJ0409, LDH-like L-MalDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

Crystallization

Crystallization on EC 1.1.1.375 - L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
determined in two crystal forms: a dimeric structure in the orthorhombic crystal at 1.9 A resolution and a tetrameric structure in the tetragonal crystal at 2.8 A
the three-dimensional structure is determined in two crystal forms: a dimeric structure in the orthorhombic crystal at 1.9 A resolution and a structure in the tetragonal crystal at 2.8 A
the three-dimensional structure of its gene product has been determined in two crystal forms: a dimeric structure in the orthorhombic crystal at 1.9 A resolution and a tetrameric structure in the tetragonal crystal at 2.8 A