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Search term: A-375 cell
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EC Number
Recommended Name
Source Tissue
Commentary
Reference
2.8.1.2
3-mercaptopyruvate sulfurtransferase
A-375 cell
-
713731
3.1.3.5
5'-nucleotidase
A-375 cell
-
728860
3.4.11.6
aminopeptidase B
A-375 cell
-
664281
3.4.22.56
caspase-3
A-375 cell
-
698197
3.4.22.61
caspase-8
A-375 cell
-
698197
3.5.1.23
ceramidase
A-375 cell
-
753979
4.4.1.1
cystathionine gamma-lyase
A-375 cell
expression of both cystathionine gamma-lyase and 3-mercaptopyruvate sulfurtransferase, the activity of 3-mercaptopyruvate sulfurtransferase is higher than that of cystathionine gamma-lyase
713731
2.7.11.20
elongation factor 2 kinase
A-375 cell
-
760309
2.3.2.5
glutaminyl-peptide cyclotransferase
A-375 cell
-
759839
1.14.11.30
hypoxia-inducible factor-asparagine dioxygenase
A-375 cell
melanoma cells
726079
4.4.1.5
lactoylglutathione lyase
A-375 cell
-
709815
3.4.24.B4
matrix metalloproteinase-13
A-375 cell
-
720440
3.4.11.2
membrane alanyl aminopeptidase
A-375 cell
-
664281
,
697497
3.4.24.80
membrane-type matrix metalloproteinase-1
A-375 cell
-
682862
2.7.12.2
mitogen-activated protein kinase kinase
A-375 cell
-
740419
2.7.11.25
mitogen-activated protein kinase kinase kinase
A-375 cell
-
740845
1.6.5.2
NAD(P)H dehydrogenase (quinone)
A-375 cell
low NQO1 activity. The redox dye 2,6-dichlorophenolindophenol may serve as a prooxidant chemotherapeutic targeting human melanoma cells in vitro and in vivo. DCPIP-apoptogenicity observed in the human melanoma cell lines A375 and G361 is inversely correlated with NAD(P)H:quinone oxidoreductase (NQO1) expression levels. 2,6-Dichlorophenolindophenol apoptogenic potency observed in human A375 and G361 melanoma cells is a function of cellular NQO1 expression levels
696140
1.14.13.39
nitric-oxide synthase (NADPH)
A-375 cell
-
745938
1.14.11.2
procollagen-proline 4-dioxygenase
A-375 cell
-
712799
3.4.25.1
proteasome endopeptidase complex
A-375 cell
-
733663
5.3.4.1
protein disulfide-isomerase
A-375 cell
-
691615
2.3.2.13
protein-glutamine gamma-glutamyltransferase
A-375 cell
-
759606
2.3.1.B41
protein-long-chain fatty-acyl-lysine deacylase (NAD+)
A-375 cell
-
756871
5.3.1.23
S-methyl-5-thioribose-1-phosphate isomerase
A-375 cell
-
705716
3.4.21.112
site-1 protease
A-375 cell
-
732292
3.6.5.2
small monomeric GTPase
A-375 cell
-
756339
2.1.1.320
type II protein arginine methyltransferase
A-375 cell
-
757401
1.14.18.1
tyrosinase
A-375 cell
-
744671
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