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Literature summary for 4.4.1.5 extracted from

  • Bair, W.B.; Cabello, C.M.; Uchida, K.; Bause, A.S.; Wondrak, G.T.
    GLO1 overexpression in human malignant melanoma (2010), Melanoma Res., 20, 85-96.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.4.1.5

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-375 cell
-
 Homo sapiens
-
G-361 cell
-
 Homo sapiens
-
melanoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methylglyoxal + glutathione
-
 Homo sapiens (R)-S-lactoylglutathione
-
 ?

Synonyms

Synonyms Comment Organism
Glo1
-
 Homo sapiens
glyoxalase I
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
glutathione
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens glyoxylase I expression is upregulated up to 10fold at the mRNA and protein level in metastatic melanoma tissue up