2.4.1.198: phosphatidylinositol N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about phosphatidylinositol N-acetylglucosaminyltransferase, go to the full flat file.

Reaction

Synonyms

acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine alpha1,6-, afpig-a, Down syndrome critical region protein 5, DR437w, Dscr5, glycosylphosphatidylinositol N-acetylglucosaminyltrans�ferase complex, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase, GntA, GPI-GlcNAc transferase, GPI-GnT, GPI-N-acetylglucosaminyltransferase, GPI-N-acetylglucosaminyltransferase complex, GPI1, GPI15, GPI19, GPI2, GPI3, phosphatidylinositol N-acetylglucosaminyltransferase subunit A, phosphatidylinositol/UDP-GlcNAc:GlcNAc transferase, PIG-A, PigA, UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.198 phosphatidylinositol N-acetylglucosaminyltransferase

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Results	in table
5	Activating Compound
2988	AA Sequence
33	Application
1	CAS Registry Number
22	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
546	Disease/ Diagnostics
2	Expression
34	General Information
5	Inhibitors
28	Localization
6	Metals/Ions
9	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
82	Organism
1	Pathway
9	pH Optimum
1	Posttranslational Modification
18	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
67	Reference
17	Source Tissue
1	Specific Activity [micromol/min/mg]
82	Substrates and Products (Substrate)
8	Subunits
113	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]

Organism

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of the Enzyme Summary Page.

Organism on EC 2.4.1.198 - phosphatidylinositol N-acetylglucosaminyltransferase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Actinobacillus succinogenes

-

685820

-

-

brenda

Aeropyrum pernix

-

685820

-

-

brenda

Alkaliphilus metalliredigens

-

685820

-

-

brenda

Arabidopsis thaliana

-

685820

-

-

brenda

Aspergillus fumigatus

2 entries

Aspergillus fumigatus YJ-407

afpig-a; Most common opportunistic fungal pathogen of human

676082

Q6Q2B4

Swissprot

brenda

Aspergillus nidulans

GPI-GlcNAc transferase subunit P; formerly Aspergillus nidulans

703326

Q5AUG0

UniProt

brenda

Bacteroides thetaiotaomicron

-

685820

-

-

brenda

Bombyx mori

-

638130

-

-

brenda

Caenorhabditis elegans

2 entries

Candida albicans

5 entries

Candida albicans ATCC MYA-2876

2 entries

Candida albicans BWP17

gene CaGPI19, encoding an accessory subunit of the enzyme complex

721539

-

-

brenda

Clostridium beijerinckii

-

685820

-

-

brenda

Clostridium tetani

-

685820

-

-

brenda

Cricetulus griseus

-

638133

-

-

brenda

Cryptosporidium parvum

-

685820

-

-

brenda

Cutibacterium acnes

-

685820

-

-

brenda

Danio rerio

-

703374

-

-

brenda

Desulfitobacterium hafniense

-

685820

-

-

brenda

Dictyostelium discoideum

-

685820

-

-

brenda

Drosophila melanogaster

-

685820

-

-

brenda

Entamoeba histolytica

-

685820

-

-

brenda

Giardia intestinalis

-

685820

-

-

brenda

Halalkalibacterium halodurans

-

685820

-

-

brenda

Homo sapiens

6 entries

Leishmania major

-

685820

-

-

brenda

Methanosarcina acetivorans

-

685820

-

-

brenda

Methanosarcina barkeri

-

685820

-

-

brenda

Methanothermobacter thermautotrophicus

-

685820

-

-

brenda

Mus musculus

4 entries

Mycobacterium sp.

-

685820

-

-

brenda

Oryza sativa

-

685820

-

-

brenda

Paramecium tetraurelia

-

685820

-

-

brenda

Plasmodium falciparum

-

685820

-

-

brenda

Pyrococcus furiosus

-

685820

-

-

brenda

Rattus norvegicus

-

685820

-

-

brenda

Saccharomyces cerevisiae

2 entries

Saccharomyces cerevisiae XM37-10c

-

638135

-

-

brenda

Schizosaccharomyces pombe

-

685820

-

-

brenda

Serratia marcescens

i.e. Serratia sp. ATCC39006

759061

Q5W254

UniProt

brenda

Thermoplasma acidophilum

-

685820

-

-

brenda

Trypanosoma brucei

3 entries

Xenopus laevis

-

703374

-

-

brenda

[Mannheimia] succiniciproducens

-

685820

-

-

brenda

Aspergillus fumigatus

afpig-a; Most common opportunistic fungal pathogen of human

676082

Q6Q2B4

Swissprot

brenda

Aspergillus fumigatus

gene gntA

736199

-

-

brenda

Caenorhabditis elegans

-

685820

-

-

brenda

Caenorhabditis elegans

gene piga-1 encoding the catalytic subunit of the phosphatidylinositol N-acetylglucosaminyltransferase complex

723140

-

-

brenda

Candida albicans

-

685820, 759489

-

-

brenda

Candida albicans

-

759489

A0A1D8PHD4, A0A1D8PKB8, Q5A6L6, Q5A9D6

UniProt

brenda

Candida albicans

enzyme complex subunit GPI2

736210

Q5A6L6

UniProt

brenda

Candida albicans

enzyme complex subunit GPI2; diverse strains

736462

Q5A6L6

UniProt

brenda

Candida albicans

gene CaGPI19, encoding an accessory subunit of the enzyme complex

721539

-

-

brenda

Candida albicans ATCC MYA-2876

-

759489

-

-

brenda

Candida albicans ATCC MYA-2876

-

759489

A0A1D8PHD4, A0A1D8PKB8, Q5A6L6, Q5A9D6

UniProt

brenda

Homo sapiens

-

638129, 638131, 638132, 638134

-

-

brenda

Homo sapiens

-

638134

Q9BRB3

SwissProt

brenda

Homo sapiens

-

638136, 685820

-

-

brenda

Homo sapiens

cDNA that encode a 71-amino acid protein, which is termed PIG-Y (for phosphatidylinositlglycan-class Y). Mouse and rice homologues of PIG-Y, exhibit 79% and 25% amino acid identity with human PIG-Y, respectively. The hydropathy profile of Saccharomyces cerevisiae´s Eri1p is quite similar to PIG-Y and the amino acid identity is 22%. N-terminus and C-terminus face the cytoplasmic side.; from the human T lymphoma KT-3 cDNA library

675882

Q3MUY2

Swissprot

brenda

Homo sapiens

gene hGPI1

638131

Q9BRB3

SwissProt

brenda

Homo sapiens

gene PIG-P

638134

P57054

SwissProt

brenda

Mus musculus

-

638133

-

-

brenda

Mus musculus

-

758711

Q64323

UniProt

brenda

Mus musculus

gene mGPI1 clone

638132

Q9QYT7

GenBank

brenda

Mus musculus

gene PIG-P

638134

Q9JHG1

Swissprot

brenda

Saccharomyces cerevisiae

-

638131, 638135, 658406, 673403, 685820, 736210

-

-

brenda

Saccharomyces cerevisiae

at least 3 components forming the enzyme complex: GPI1, GPI2 or PIG-C, GPI3 or PIG-A

638135

-

-

brenda

Trypanosoma brucei

-

685820

-

-

brenda

Trypanosoma brucei

cloned variant ILTat 1.3, isolated from rat blood

288963

-

-

brenda

Trypanosoma brucei

variant MITat 1.4

638128

-

-

brenda