2.4.1.198: phosphatidylinositol N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about phosphatidylinositol N-acetylglucosaminyltransferase, go to the full flat file.

Reaction

Synonyms

acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine alpha1,6-, afpig-a, Down syndrome critical region protein 5, DR437w, Dscr5, glycosylphosphatidylinositol N-acetylglucosaminyltrans�ferase complex, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase, GntA, GPI-GlcNAc transferase, GPI-GnT, GPI-N-acetylglucosaminyltransferase, GPI-N-acetylglucosaminyltransferase complex, GPI1, GPI15, GPI19, GPI2, GPI3, phosphatidylinositol N-acetylglucosaminyltransferase subunit A, phosphatidylinositol/UDP-GlcNAc:GlcNAc transferase, PIG-A, PigA, UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.198 phosphatidylinositol N-acetylglucosaminyltransferase

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Results	in table
5	Activating Compound
2988	AA Sequence
33	Application
1	CAS Registry Number
22	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
546	Disease/ Diagnostics
2	Expression
34	General Information
5	Inhibitors
28	Localization
6	Metals/Ions
9	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
82	Organism
1	Pathway
9	pH Optimum
1	Posttranslational Modification
18	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
67	Reference
17	Source Tissue
1	Specific Activity [micromol/min/mg]
82	Substrates and Products (Substrate)
8	Subunits
113	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]

Inhibitors

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Inhibitors on EC 2.4.1.198 - phosphatidylinositol N-acetylglucosaminyltransferase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

iodoacetic acid

Trypanosoma brucei

-

-

638128

N-ethylmaleimide

Trypanosoma brucei

-

binding site is close or at the active site, UDP-N-acetyl-D-glucosamine protects; strong

638128

p-chloromercuriphenylsulfonic acid

Trypanosoma brucei

-

-

638128

SH-alkylating reagents

Trypanosoma brucei

-

-

638128

-

additional information

Saccharomyces cerevisiae

-

GTP-bound Ras2 protein associates in vivo with enzyme complex and inhibits its activity. Ras2 associates with enzyme complex subunit Eri1

658406

-