2.3.1.86: fatty-acyl-CoA synthase system
This is an abbreviated version!
For detailed information about fatty-acyl-CoA synthase system, go to the full flat file.
Word Map on EC 2.3.1.86
-
2.3.1.86
-
udp-glucuronosyltransferase
-
glucuronidation
-
farnesoid
-
carvedilol
-
extrahepatic
-
acid-conjugating
-
parapsilosis
-
hyodeoxycholic
-
4-hydroxyestrone
-
analysis
-
medicine
-
biofuel production
- 2.3.1.86
-
udp-glucuronosyltransferase
-
glucuronidation
-
farnesoid
- carvedilol
-
extrahepatic
-
acid-conjugating
- parapsilosis
-
hyodeoxycholic
- 4-hydroxyestrone
- analysis
- medicine
- biofuel production
Reaction
+ 7 malonyl-CoA + 14 NADPH + 14 H+ = + 7 CoA + 7 CO2 + 14 NADP+ + 7 H2O
Synonyms
CpFas2, FAS, FAS1, fas2, fatty acid synthase, fatty-acyl-CoA synthase, yeast fatty acid synthase
ECTree
Advanced search results
Systematic Name
Systematic Name on EC 2.3.1.86 - fatty-acyl-CoA synthase system
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)
The enzyme from yeasts (Ascomycota and Basidiomycota) is a multi-functional protein complex composed of two subunits. One subunit catalyses the reactions EC 1.1.1.100, 3-oxoacyl-[acyl-carrier-protein] reductase and EC 2.3.1.41, beta-ketoacyl-[acyl-carrier-protein] synthase I, while the other subunit catalyses the reactions of EC 2.3.1.38, [acyl-carrier-protein] S-acetyltransferase, EC 2.3.1.39, [acyl-carrier-protein] S-malonyltransferase, EC 4.2.1.59, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, EC 1.3.1.10, enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) and EC 1.1.1.279, (R)-3-hydroxyacid-ester dehydrogenase. The enzyme system differs from the animal system (EC 2.3.1.85, fatty-acid synthase system) in that the enoyl reductase domain requires FMN as a cofactor, and the ultimate product is an acyl-CoA (usually palmitoyl-CoA) instead of a free fatty acid.