2.3.1.86: fatty-acyl-CoA synthase system
This is an abbreviated version!
For detailed information about fatty-acyl-CoA synthase system, go to the full flat file.
Word Map on EC 2.3.1.86
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2.3.1.86
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udp-glucuronosyltransferase
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glucuronidation
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farnesoid
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carvedilol
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extrahepatic
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acid-conjugating
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parapsilosis
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hyodeoxycholic
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4-hydroxyestrone
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analysis
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medicine
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biofuel production
- 2.3.1.86
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udp-glucuronosyltransferase
-
glucuronidation
-
farnesoid
- carvedilol
-
extrahepatic
-
acid-conjugating
- parapsilosis
-
hyodeoxycholic
- 4-hydroxyestrone
- analysis
- medicine
- biofuel production
Reaction
Synonyms
CpFas2, FAS, FAS1, fas2, fatty acid synthase, fatty-acyl-CoA synthase, yeast fatty acid synthase
ECTree
2.3.1.86 fatty-acyl-CoA synthase systemAdvanced search results
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results (Inhibitors
Inhibitors on EC 2.3.1.86 - fatty-acyl-CoA synthase system
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
p-chloromercuribenzoate
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complete inhibition of type II fatty acid synthase at 1 mM
thiolactomycin
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antibiotic and it's analogues, 50% inhibition of the overall activity at 0.17 mM, effect of antibiotic on compounds of the enzyme
1,3-Dibromo-2-propanone
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complete inhibition at 0.005 mM after 1 min, cross-links alpha-, not beta-subunits, inhibits only beta-ketoacyl synthetase reaction, acetyl-CoA prevents, malonyl-CoA prevents only slightly
5,5'-dithio-bis(2-nitrobenzoic acid)
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covalent binding to palmitoyl residues, malonyl-CoA protects
iodoacetamide
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beta-ketoacyl synthetase; no inhibition of acetyl transferase activity
iodoacetamide
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no inhibition of acetyl transferase activity; pH-independent between 5.0 and 9.0
N-ethylmaleimide
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complete inhibition of type II fatty acid synthase at 1 mM
N-ethylmaleimide
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no inhibition of acetyl transferase activity; pH-dependent
