2.3.1.65: bile acid-CoA:amino acid N-acyltransferase
This is an abbreviated version!
For detailed information about bile acid-CoA:amino acid N-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.65
-
2.3.1.65
-
peroxisomal
-
unconjugated
-
acyl-coas
-
thioesterases
-
cholyl-coa
-
acid-conjugating
-
hbats
-
gallbladder
-
proliferator
- 2.3.1.65
- peroxisomal
-
unconjugated
- acyl-coas
-
thioesterases
- cholyl-coa
-
acid-conjugating
-
hbats
- gallbladder
- proliferator
Reaction
Synonyms
acyltransferase, glycine-taurine N-, amino acid N-choloyltransferase, BAAT, BAATP1, BACAT, BAT, bile acid CoA: amino acid N-acyltransferase, bile acid CoA:amino acid N-acyltransferase, bile acid CoA:N-acyltransferase, bile acid coenzyme A-amino acid N-acyltransferase, bile acid coenzyme A: amino acid N-acyltransferase, bile acid coenzyme A:amino acid N-acyltransferase, bile acid-CoA:amino acid N acyltransferase, bile acid-CoA:amino acid N-acyltransferase, bile acid–coenzyme A:amino acid N-acyltransferase, glycine-taurine N-acyltransferase, hBAT, mBAT, rBAT
ECTree
Advanced search results
Systematic Name
Systematic Name on EC 2.3.1.65 - bile acid-CoA:amino acid N-acyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
choloyl-CoA:glycine N-choloyltransferase
Also acts on CoA derivatives of other bile acids. Taurine and 2-fluoro-beta-alanine can act as substrates, but more slowly [4]. The enzyme can also conjugate fatty acids to glycine and can act as a very-long-chain acyl-CoA thioesterase [7]. Bile-acid---amino-acid conjugates serve as detergents in the gastrointestinal tract, solubilizing long chain fatty acids, mono- and diglycerides, fat-soluble vitamins and cholesterol [4]. This is the second enzyme in a two-step process leading to the conjugation of bile acids with amino acids; the first step is the conversion of bile acids into their acyl-CoA thioesters, which is catalysed by EC 6.2.1.7, cholate---CoA ligase.