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2.3.1.65: bile acid-CoA:amino acid N-acyltransferase

This is an abbreviated version!
For detailed information about bile acid-CoA:amino acid N-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.65

Reaction

choloyl-CoA
+
glycine
=
CoA
+
glycocholate

Synonyms

acyltransferase, glycine-taurine N-, amino acid N-choloyltransferase, BAAT, BAATP1, BACAT, BAT, bile acid CoA: amino acid N-acyltransferase, bile acid CoA:amino acid N-acyltransferase, bile acid CoA:N-acyltransferase, bile acid coenzyme A-amino acid N-acyltransferase, bile acid coenzyme A: amino acid N-acyltransferase, bile acid coenzyme A:amino acid N-acyltransferase, bile acid-CoA:amino acid N acyltransferase, bile acid-CoA:amino acid N-acyltransferase, bile acid–coenzyme A:amino acid N-acyltransferase, glycine-taurine N-acyltransferase, hBAT, mBAT, rBAT

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.65 bile acid-CoA:amino acid N-acyltransferase

Reference

Reference on EC 2.3.1.65 - bile acid-CoA:amino acid N-acyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vessey, D.A.
The co-purification and common identity of cholyl CoA:glycine- and cholyl CoA: taurine-N-acyltransferase activities from bovine liver
J. Biol. Chem.
254
2059-2063
1979
Bos taurus
Manually annotated by BRENDA team
Czuba, B.; Vessey, D.A.
Kinetic characterization of cholyl-CoA glycine-taurine N-acyltransferase from bovine liver
J. Biol. Chem.
255
5296-5299
1980
Bos taurus
Manually annotated by BRENDA team
Czuba, B.; Vessey, D.A.
Structural characterization of cholylcoenzyme A: glycine-taurine N-acyltransferase and a covalent substrate intermediate
J. Biol. Chem.
261
6260-6263
1986
Bos taurus
Manually annotated by BRENDA team
Kimura, M.; Okuno, E.; Inada, J.; Ohyama, H.; Kido, R.
Purification and characterization of amino-acid N-choloyltransferase from human liver
Hoppe-Seyler's Z. Physiol. Chem.
364
637-645
1983
Homo sapiens
Manually annotated by BRENDA team
Killenberg, P.G.; Jordan, J.T.
Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from rat liver
J. Biol. Chem.
253
1005-1010
1978
Rattus norvegicus
Manually annotated by BRENDA team
Czuba, B.; Vessey, D.A.
Identification of a unique mammalian species of cholyl-CoA: amino acid N-acyltransferase
Biochim. Biophys. Acta
665
612-614
1981
Canis lupus familiaris
Manually annotated by BRENDA team
Poley, J.R.; Dower, J.C.; Owen, J.R.; Owen C.A.; Stickler, G.B.
Bile acids in infants and children
J. Lab. Clin. Med.
63
838-846
1964
Gallus gallus
Manually annotated by BRENDA team
Ide, T.; Kano, S.; Murata, M.; Yanagita, T.; Sugano, M.
Dietary modifications of the biliary bile acid glycine:taurine ratio and activity of hepatic bile acid-CoA:amino acid N-acyltransferase (EC 2.3.1) in the rat
Br. J. Nutr.
72
93-100
1994
Rattus norvegicus
Manually annotated by BRENDA team
Sfakianos, M.K.; Wilson, L.; Sakalian, M.; Falany, C.N.; Barnes, S.
Conserved residues in the putative catalytic triad of human bile acid coenzyme A:amino acid N-acyltransferase
J. Biol. Chem.
277
47270-47275
2002
Homo sapiens
Manually annotated by BRENDA team
Falany, C.N.; Fortinberry, H.; Leiter, E.H.; Barnes, S.
Cloning, expression, and chromosomal localization of mouse liver bile acid CoA:amino acid N-acyltransferase
J. Lipid Res.
38
1139-1148
1997
Mus musculus
Manually annotated by BRENDA team
O'Byrne, J.; Hunt, M.C.; Rai, D.K.; Saeki, M.; Alexson, S.E.H.
The Human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine
J. Biol. Chem.
278
34237-34244
2003
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
He, D.; Barnes, S.; Falany, C.N.
Rat liver: Expression, characterization, and peroxisomal localization
J. Lipid Res.
44
2242-2249
2003
Rattus norvegicus
Manually annotated by BRENDA team
Pellicoro, A.; van den Heuvel, F.A.; Geuken, M.; Moshage, H.; Jansen, P.L.; Faber, K.N.
Human and rat bile acid-CoA:amino acid N-acyltransferase are liver-specific peroxisomal enzymes: implications for intracellular bile salt transport
Hepatology
45
340-348
2007
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Shonsey, E.M.; Sfakianos, M.; Johnson, M.; He, D.; Falany, C.N.; Falany, J.; Merkler, D.J.; Barnes, S.
Bile acid coenzyme A: amino acid N-acyltransferase in the amino acid conjugation of bile acids
Methods Enzymol.
400
374-394
2005
Homo sapiens (Q14032), Rattus norvegicus
Manually annotated by BRENDA team
Tougou, K.; Fukuda, T.; Ito, T.; Yamazaki, H.; Fujio, Y.; Azuma, J.
Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals
Drug Metab. Pharmacokinet.
22
125-128
2007
Homo sapiens
Manually annotated by BRENDA team
Shonsey, E.M.; Eliuk, S.M.; Johnson, M.S.; Barnes, S.; Falany, C.N.; Darley-Usmar, V.M.; Renfrow, M.B.
Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal
J. Lipid Res.
49
282-294
2008
Homo sapiens
Manually annotated by BRENDA team
Chen, Y.H.; Hong, I.C.; Kuo, K.K.; Hsu, H.K.; Hsu, C.
Role of retinoid-X receptor-alpha in the suppression of rat bile acid coenzyme A-amino acid N-acyltransferase in liver during sepsis
Shock
28
65-70
2007
Rattus norvegicus
Manually annotated by BRENDA team
Buch, C.; Hunt, M.C.; Alexson, S.E.; Hallberg, E.
Localization of peroxisomal matrix proteins by photobleaching
Biochem. Biophys. Res. Commun.
388
355-359
2009
Homo sapiens
Manually annotated by BRENDA team
Chen, B.C.; Kuo, K.K.; Chen, K.Y.; Liu, C.H.; Tsai, L.Y.; Hsu, H.K.; Hsu, C.
Retinoid X receptor alpha participation in dexamethasone-induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver
Shock
32
164-171
2009
Rattus norvegicus
Manually annotated by BRENDA team
Kirilenko, B.M.; Hagey, L.R.; Barnes, S.; Falany, C.N.; Hiller, M.
Evolutionary analysis of bile acid-conjugating enzymes reveals a complex duplication and reciprocal loss history
Genome Biol. Evol.
11
3256-3268
2019
Bos taurus, Felis catus, Homo sapiens, Mus musculus, Loxodonta africana
Manually annotated by BRENDA team
Fang, W.; Zhang, L.; Meng, Q.; Wu, W.; Lee, Y.K.; Xie, J.; Zhang, H.
Effects of dietary pectin on the profile and transport of intestinal bile acids in young pigs
J. Anim. Sci.
96
4743-4754
2018
Sus scrofa
Manually annotated by BRENDA team
Styles, N.A.; Shonsey, E.M.; Falany, J.L.; Guidry, A.L.; Barnes, S.; Falany, C.N.
Carboxy-terminal mutations of bile acid CoA N-acyltransferase alter activity and substrate specificity
J. Lipid Res.
57
1133-1143
2016
Homo sapiens
Manually annotated by BRENDA team