2.1.1.157: sarcosine/dimethylglycine N-methyltransferase
This is an abbreviated version!
For detailed information about sarcosine/dimethylglycine N-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.157
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2.1.1.157
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s-adenosylmethionine
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methanohalophilus
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osmolyte
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portucalensis
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methyltransferases
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methanoarchaeon
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adomet
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drought
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ectothiorhodospira
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s-adenosylhomocysteine
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choline
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three-step
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biotechnology
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nutrition
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agriculture
- 2.1.1.157
- s-adenosylmethionine
-
methanohalophilus
-
osmolyte
- portucalensis
- methyltransferases
-
methanoarchaeon
- adomet
- drought
-
ectothiorhodospira
- s-adenosylhomocysteine
- choline
-
three-step
- biotechnology
- nutrition
- agriculture
Reaction
2 S-adenosyl-L-methionine + = 2 S-adenosyl-L-homocysteine +
Synonyms
dimethylglycine methyltransferase, DMT, DMT2, glycine sarcosine dimethylglycine methyltransferase, glycine sarcosine methyltransferase, GSDMT, GsSDMT, MXAN 3190, sarcosine dimethylglycine methyltransferas, sarcosine dimethylglycine methyltransferase, sarcosine dimethylglycine N-methyltransferase, Sdm, Sdm homologue protein, SdmA, SDMT
ECTree
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Engineering
Engineering on EC 2.1.1.157 - sarcosine/dimethylglycine N-methyltransferase
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M172R
site-directed mutagenesis, reduced activity with sarcosine, but highly reduced activity with dimethylglycine compared to the wild-type enzyme
P171Q
site-directed mutagenesis, reduced activity with sarcosine and dimethylglycine compared to the wild-type enzyme
P171Q/M172R
site-directed mutagenesis, reduced activity with glycine and sarcosine, but highly reduced activity with dimethylglycine compared to the wild-type enzyme
additional information
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construction of a chromosomal sdmA gene disruption knockout mutant, phenotype, overview