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1.1.1.25: shikimate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about shikimate dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.25

Reaction

shikimate
+
NADP+
=
3-dehydroshikimate
 +
NADPH
 +
H+

Synonyms

3-dehydroquinate dehydratase/shikimate dehydrogenase, 5-dehydroshikimate reductase, 5-dehydroshikimic reductase, ael1, Af2327, AroE, bifunctional dehydroquinate dehydratase-shikimate dehydrogenase, bifunctional DHQD-SDH/QDH, cgR_0495, cgR_1677, ChlreSDH, CsDQD/SDH, dehydroquinate dehydratase-shikimate dehydrogenase, dehydroquinate dehydratase/shikimate dehydrogenase, dehydroshikimic reductase, DHD/SHD, DHQ-SDH, DHQD-SDH, DHS reductase, DQD/SDH, EcDQD, EcDQD/SDH, EcDQD/SDH1, EcDQD/SDH2, EcDQD/SDH3, EcoSDH, EcSDH, EMB3004, HI0607, HpSDH, More, MtbSD, MtbSDH, NAD+-dependent enzyme quinate/shikimate dehydrogenase, NADP-dependent shikimate dehydrogenase, NADP-shikimate dehydrogenase, PgSDH, PhypaSDH, PintaSDH, Poptr1, Poptr5, PoptrSDH1, QDH/SDH, qsuD, quinate/shikimate dehydrogenase, RhobaSDH, rifI, SaSDH, SD, SDH, sdhL, SelmoSDH, ShDH, shikimate 5-dehydrogenase, shikimate dehydrogenase, shikimate oxidoreductase, shikimate:NADP oxidoreductase, shikimate:NADP+ 5-oxidoreductase, shikimate:NADP+ oxidoreductase, SKDH, TgSDH, tm0346, VvSDH1, VvSDH2, VvSDH3, VvSDH4, YdiB

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.25 shikimate dehydrogenase (NADP+)

KI Value

KI Value on EC 1.1.1.25 - shikimate dehydrogenase (NADP+)

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.458
(3R,3'R,4S,4'S,5R,5'R)-N,N'-(butane-1,4-diyl)bis(3,4,5-trihydroxycyclohex-1-ene-1-carboxamide)
potassium phosphate buffer, pH 7.5, 25°C, cofactor NADPH
0.416
(3R,3'R,4S,4'S,5R,5'R)-N,N'-(ethane-1,2-diyl)bis(3,4,5-trihydroxycyclohex-1-ene-1-carboxamide)
25°potassium phosphate buffer, pH 7.5, 25°C, cofactor NADPH
0.4
(3R,3'R,4S,4'S,5R,5'R)-N,N'-(propane-1,3-diyl)bis(3,4,5-trihydroxycyclohex-1-ene-1-carboxamide)
potassium phosphate buffer, pH 7.5, 25°C, cofactor NADPH
0.733
(3R,4S,5R)-3,4,5-trihydroxy-N-(3-hydroxypropyl)cyclohex-1-ene-1-carboxamide
potassium phosphate buffer, pH 7.5, 25°C, cofactor NADPH
0.717
(3R,4S,5R)-3,4,5-trihydroxy-N-(4-hydroxybutyl)cyclohex-1-ene-1-carboxamide
potassium phosphate buffer, pH 7.5, 25°C, cofactor NADPH
0.642
(3R,4S,5R)-3,4,5-trihydroxy-N-(5-hydroxypentyl)cyclohex-1-ene-1-carboxamide
potassium phosphate buffer, pH 7.5, 25°C, cofactor NADPH
0.587
(3R,4S,5R)-3,4,5-trihydroxy-N-(6-hydroxyhexyl)cyclohex-1-ene-1-carboxamide
potassium phosphate buffer, pH 7.5, 25°C, cofactor NADPH
0.075 - 0.246
1,3-benzodioxole-5-carbothioamide
0.083 - 0.213
5-[4-(1H-imidazol-2-ylcarbonyl)phenyl]thiophene-2-carboxylic acid
0.046 - 0.101
6-amino-1,2,3,4-tetrahydronaphthalen-1-one
0.0083 - 0.0103
[4-(4-methylperhydro-1,4-diazepin-1-yl)phenyl]methanol
additional information
additional information
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