Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
1 different search results found


Details for hypoxia-inducible factor-1alpha signaling pathway
Gene ontology ID
GO:0097411
Definition
A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia
Synonyms
1. HIF1alpha pathway
2. hypoxia-inducible factor signaling
3. hypoxia-inducible factor-1alpha signalling pathway
References
1. GOC: bf
2. GOC: jc
3. http www.sabiosciences.com/pathway.php?sn=HIF1Alpha_Pathway
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
Tree view
Gene ontology