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Gene ontology
Version 2014-12-22
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Details for lyase activity
4.-.-.-, 4
Gene ontology ID
GO:0016829
Definition
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring
Comment
Note that enzymes of class EC:4.99.-.- should also be annotated to this term.
Synonyms
1. other lyase activity
References
1. EC 4.-.-.-
2. ISBN 0198547684
3. EC 4
4. Reactome: R-HSA-5696408 "PHYKPL tetramer hydrolyses 5PHL"
5. Reactome: R-HSA-6782895 "TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)"
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Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
lyase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
Atg8 ligase activity is a
CDP-alcohol phosphotransferase activity is a
glucanosyltransferase activity is a
Kdo transferase activity is a
mannosylphosphate transferase activity is a
molybdopterin molybdotransferase activity is a
transferase activity, transferring acyl groups is a
transferase activity, transferring aldehyde or ketonic groups is a
transferase activity, transferring alkyl or aryl (other than methyl) groups is a
transferase activity, transferring glycosyl groups is a
transferase activity, transferring nitrogenous groups is a
amidinotransferase activity is a
archaeosine synthase activity is a
glycine amidinotransferase activity is a
scyllo-inosamine-4-phosphate amidinotransferase activity is a
dATP(dGTP)-DNA purinetransferase activity is a
oximinotransaminase activity is a
pyridoxine 5'-phosphate synthase activity is a
transaminase activity is a
transferase activity, transferring one-carbon groups is a
transferase activity, transferring phosphorus-containing groups is a
transferase activity, transferring selenium-containing groups is a
transferase activity, transferring sulfur-containing groups is a
UDP-L-rhamnose synthase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a